July 2023 in “IntechOpen eBooks” Some types of hair loss can be reversed, others are permanent, and treatments vary by type.
24 citations
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January 2006 in “Skin Pharmacology and Physiology” This study found that finasteride (1 mg/day) appeared to reverse the shortening of the hair cycle in androgen sensitive sites but did not convert miniaturized hair into terminal hair.
4 citations
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November 1981 in “Indian Journal of Dermatology Venereology and Leprology” This study observed that oral calcium pantothenate may reverse hair greying in some adolescent cases, as seen in two girls whose grey hairs turned black after treatment.
3 citations
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February 2023 in “Journal of Experimental Pharmacology” This study found that LHE may prevent and reverse testosterone-induced prostatic hyperplasia, supporting the traditional use of Kigelia africana for some reproductive system disorders.
3 citations
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January 2017 in “Yonsei Medical Journal” This study found that inhibiting 11β-HSD1 can partially reverse the negative impact of glucocorticoids on dermal papilla cells in human scalps, suggesting potential for treating stress-related hair loss.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that the multifunctional exosome-based delivery platform EX104 reversed hair follicle miniaturization and promoted hair growth in a mouse model of androgenetic alopecia, performing comparably to minoxidil while also enhancing capillary growth and follicular proliferation.
February 2020 in “Definitions” This article discusses a proprietary botanical lotion with potential to reverse chemotherapy-induced alopecia, restore hair cycles, and improve patient wellbeing; however, it reports no new clinical results.
April 2018 in “Journal of Investigative Dermatology” This study found that the PPAR-γ modulator AGED can reverse epithelial-mesenchymal transition in hair follicles affected by lichen planopilaris ex vivo, suggesting potential for treating scarring alopecias.
June 2007 in “Endocrinology and Metabolism Clinics of North America” This study reports that incomplete information in a reverse supply chain can lead to efficiency losses, but a two-part tariff contract for the remanufacturer may improve performance by eliciting private information from collectors.
77 citations
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August 1986 in “Archives of Dermatology” This report describes a case in which intramuscular cyanocobalamin treatment reversed skin and nail pigmentation changes and premature gray hair caused by vitamin B12 deficiency due to pernicious anemia.
15 citations
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May 2003 in “American Journal of Kidney Diseases” This case report describes a hemodialysis patient whose hair loss reversed after switching from tinzaparin to enoxaparin, suggesting tinzaparin-induced alopecia.
14 citations
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July 1977 in “Archives of Dermatology” This case report found that a linoleic acid topical application reversed essential fatty acid deficiency and improved scalp dermatitis, alopecia, and hair depigmentation in a 19-year-old patient on fat-free intravenous nutrition.
4 citations
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March 2010 in “International Journal of Oral Science” This study concluded that the Chinese herbal medicine Xianhuayin effectively reversed DMBA-induced premalignant lesions in the buccal pouch of golden hamsters.
116 citations
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September 2001 in “Journal of The American Academy of Dermatology” This study suggests that miniaturization in pattern hair loss may occur abruptly and can be reversed with treatment, as supported by histologic evidence in finasteride-responsive patients.
71 citations
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October 2017 in “Journal of Investigative Dermatology” PPAR-γ agonists like pioglitazone may help manage lichen planopilaris but don't fully reverse scarring.
37 citations
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March 2009 in “Hair transplant forum international” This small study observed that infusing platelet rich plasma into the scalp reversed hair miniaturization and stimulated new hair growth in patients with androgenetic alopecia and alopecia areata over 8 months.
14 citations
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July 1977 in “PubMed” This study reported that a 19-year-old man's essential fatty acid deficiency was reversed with daily topical application of linoleic acid, improving clinical symptoms and normalizing certain fatty acid levels.
February 2024 in “Molecules/Molecules online/Molecules annual” In this study, NMN was found to reverse hair follicle atrophy, thinning, and sparsity in mice induced by DHT, and significantly decreased DHT-induced inflammation and oxidative stress in cultured human dermal papilla cells, enhancing hair growth-related markers.
July 2022 in “Journal of Investigative Dermatology” The combination of a plant extract and a peptide can increase hair pigmentation and may reverse greying.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that gene therapy using a mouse cytomegalovirus vector with telomerase reverse transcriptase or follistatin significantly extended lifespan and improved health markers in mice, without adverse effects.
This study found that oral Finasteride therapy at doses of 1-5mg can significantly reverse hair loss in men with androgenic alopecia.
November 2003 in “Aap Grand Rounds” This study found that a combination of low-dose flutamide and metformin therapy may reverse insulin resistance and reduce fat mass in nonobese adolescents with PCOS.
73 citations
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July 1977 in “Archives of Dermatology” In this case report, applying linoleic acid topically reversed essential fatty acid deficiency and related skin symptoms in a patient receiving long-term fat-free intravenous nutrition.
4 citations
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October 2003 in “PubMed” This study in a rat model found that dietary rehabilitation with a high protein diet reversed symptoms of kwashiorkor, suggesting a role for free radicals in its development.
1 citations
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January 2017 in “Journal of Clinical and Diagnostic Research” This case series reported three instances where alopecia linked to sodium valproate was reversed after discontinuing the drug.
March 2024 in “Cancer Research” This study found that eliminating senescent cells using senolytic drugs effectively prevented and reversed paclitaxel-induced peripheral neuropathy in mice.
January 2020 in “International Journal of Trichology” This case study reported two instances of female androgenetic alopecia with male pattern reversed after surgical removal of an ovarian tumor.
180 citations
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January 2003 in “American Journal of Clinical Dermatology” This article reviews the effects of menopause on skin aging and suggests that hormone replacement therapy may help reverse some of these changes.
52 citations
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January 1999 in “Journal of Small Animal Practice” This case study of a cat with pancreatic carcinoma and paraneoplastic alopecia found that removing the internal tumor reversed hair loss, but symptoms reappeared as the cancer metastasized.
40 citations
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January 1996 in “Journal of Dermatological Treatment” This study found that using an antimicrobial lotion for 18 months may reduce inflammation and potentially partially reverse hair loss in men with androgenetic alopecia.