Reversible Hyperpigmentation of Skin and Nails With White Hair Due to Vitamin B12 Deficiency

    August 1986 in “ Archives of Dermatology ”
    Nopadon Noppakun
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    Studysummary This report describes a case in which intramuscular cyanocobalamin treatment reversed skin and nail pigmentation changes and premature gray hair caused by vitamin B12 deficiency due to pernicious anemia.
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    A case study from 1986 reported reversible generalized hyperpigmentation of the skin and nails, along with premature gray hair, due to vitamin B12 deficiency caused by pernicious anemia. The patient's skin and hair pigmentation returned to normal following treatment with intramuscular cyanocobalamin.
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