Reversible Facial Hyperpigmentation Associated With Vitamin B12 Deficiency
October 2016
in “
Nutrition in clinical practice
”
TLDR Vitamin B12 deficiency can cause facial dark spots that go away with treatment.
The document reported a rare case of reversible melasma-like cutaneous hyperpigmentation associated with vitamin B12 deficiency, specifically pernicious anemia. The patient exhibited localized hyperpigmentation on the face, which is less commonly described compared to generalized hyperpigmentation. The study highlighted the importance of recognizing vitamin B12 deficiency as a potential cause of hyperpigmentation and discussed possible mechanisms behind this association. The condition was reversible upon treatment of the vitamin B12 deficiency.
