January 2022 in “Tissue & Cell” Using both platelet-rich plasma and minoxidil together gives the best results for hair growth in male rats with hair loss.
October 2023 in “IBRO neuroscience reports” Rat hair follicle stem cells have functional oxytocin receptors, useful for studying neuropsychiatric disorders.
45 citations,
October 2014 in “Stem cell research & therapy” Modified rat stem cells on a special scaffold improved blood vessel formation and wound healing in skin substitutes.
Transplanted rat hair follicles grew hair and had increased but not fully restored nerve connections in mice.
291 citations,
October 2005 in “Proceedings of the National Academy of Sciences of the United States of America” Adult stem cells from rat whisker follicles can regenerate hair follicles and sebaceous glands.
116 citations,
August 2010 in “Nature” Scientists turned rat thymus cells into stem cells that can help repair skin and hair.
37 citations,
January 1991 in “Reproductive Toxicology” Finasteride reduces male rat fertility by causing issues with copulatory plug formation.
18 citations,
June 2002 in “BJUI” Finasteride doesn't change rat testicle weight or sperm production.
7 citations,
January 1982 in “Australian Journal of Biological Sciences” Epithelial cells from young rat hair follicles grow and form aggregates in culture, but don't produce hair keratin proteins.
5 citations,
January 2023 in “Cell proliferation” Chick embryo extract helps rat hair follicle stem cells potentially turn into Schwann cells, important for the nervous system.
4 citations,
October 2020 in “Toxicology Mechanisms and Methods” Hesperidin protects rat testicles from finasteride damage and improves sperm health.
3 citations,
August 2018 in “Deleted Journal” Guasha changed rat skin appearance and blood vessels temporarily without affecting certain nerve proteins or fiber structure.
1 citations,
December 2015 in “The Egyptian Journal of Histology” Hypothyroidism harms rat skin, but topical triiodothyronine may help improve it.
Dutasteride did not change rat spermatogenesis or oxidative stress but needs more research.
53 citations,
January 1986 in “Endocrinology” Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.
6 citations,
July 2018 in “Scientific Reports” Methamphetamine affects gene expression in rat whisker follicles, with key genes linked to addiction.
1 citations,
August 2022 in “International journal of biological and chemical sciences” Iodine-deficient diets and antithyroid substances affected rat growth and behavior, but most adapted with positive weight gain.
1 citations,
June 2022 in “Frontiers in Neuroanatomy” Early hormones shape sex-specific differences in rat glands.
April 2020 in “Archivos españoles de urología” Dutasteride does not seem to change rat spermatogenesis or oxidative stress.
February 2020 in “Journal of chemical neuroanatomy” Researchers found a way to make rat hair follicle cells start turning into motor neuron-like cells, but couldn't fully turn them into working motor neurons.
March 2018 in “International Pharmacy Acta” New niosomal formulation effectively delivers aminexil through rat skin.
September 2012 in “The Egyptian Journal of Histology” Flutamide caused damage to male rat reproductive organs and may affect fertility.
17 citations,
December 2001 in “Journal of Investigative Dermatology” The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.
7 citations,
June 2015 in “The American Journal of the Medical Sciences” Finasteride helps reduce blood vessel growth in diabetic rat kidneys.
6 citations,
July 2018 in “Steroids” Testosterone changes how certain channels work in male rat reproductive tracts, affecting fertility-related fluid balance.
5 citations,
January 2016 in “Asian pacific Journal of Tropical Biomedicine” Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.
December 2023 in “Annales Pharmaceutiques Françaises” The UV–Vis Spectrophotometry method effectively measures minoxidil in rat skin for alopecia treatment.
January 2022 in “Social Science Research Network” Potassium channel modulators mostly increase the activity of rat whisker mechanoreceptors.
2 citations,
July 2009 in “Pharmacognosy Research” A herbal mix with chickpea, holy basil, and nut grass extracts grew rat hair well, similar to a common hair growth drug.
149 citations,
September 2017 in “Pharmaceutics” Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.