Sub-Chronic Effects of a Phthirusa Pyrifolia Aqueous Extract on Reproductive Function and Comparative Hormone Levels in Male Rats
March 2016
in “
Asian pacific Journal of Tropical Biomedicine
”
TLDR Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.
The study examined the effects of Phthirusa pyrifolia aqueous extract on male reproductive function in rats. Thirty rats were divided into three groups, with one receiving water, another treated with finasteride, and the third given the extract. The extract led to significant changes in testicular structure and a substantial decrease in testosterone levels by approximately 81.88% compared to the control group. It did not cause liver or kidney damage, suggesting hepato-protective properties. The study concluded that the extract may reduce libido and reproductive capabilities in rats due to its high flavonoid content. However, the number of rats used in the study was not specified in the provided text.
