The Effect of Experimental Hypothyroidism on the Skin of Adult Male Albino Rats and the Therapeutic Role of Topical Triiodothyronine

    December 2015 in “ The Egyptian Journal of Histology ”
    Sally A. Selim, Zeinab M. Alazouny
    Studysummary This study found that experimentally induced hypothyroidism in rats is associated with impaired skin structure, but topical application of triiodothyronine (T3) improved these changes to resemble normal skin.
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    Research cited in this study 7

    1. Thyroid Hormone and Wound Healing Journal of Thyroid Research · 2013
    2. Thyroid Hormone Action on Skin Dermato-endocrinology · 2011
    3. Thyroid-Stimulating Hormone: A Novel, Locally Produced Modulator of Human Epidermal Functions, Regulated by Thyrotropin-Releasing Hormone and Thyroid Hormones Endocrinology · 2010
    4. Exploring the Thyroid-Skin Connection: Concepts, Questions, and Clinical Relevance Journal of Investigative Dermatology · 2009
    5. Repigmentation of Gray Hair After Thyroid Hormone Treatment Actas Dermo-Sifiliográficas · 2007
    6. Scratching the Surface of Skin Development Nature · 2007
    7. Thyroid Hormone Receptor β1 Is Expressed in the Human Hair Follicle British journal of dermatology/British journal of dermatology, Supplement · 2000