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Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.

Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.

Skin stem cells can help improve skin repair and regeneration.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

Different fish use the same genes to regrow teeth.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

Removing the VDR gene in skin cells reduces their growth and affects hair-related genes.

Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.

Male pattern baldness is often genetic and linked to a hormone, with treatments like finasteride and minoxidil being effective for some men.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Runx1 affects hair growth, cancer development, and autoimmune diseases in epithelial tissues.

Wound healing can help prevent hair loss from chemotherapy in young rats by increasing interleukin-1β signaling.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Melanoblasts migrate to the skin using various pathways, and understanding this process could help with skin disease research.

Eating fewer calories improves the ability of stem cells to repair and renew the body in various tissues.

Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.

High ornithine decarboxylase levels may lead to hair loss and cancer by increasing CK2 activity in the nucleus.

Scalp cooling is the only FDA-approved method to prevent hair loss from chemotherapy, but other treatments like minoxidil and PRP are being tested.

Androgenetic alopecia is mainly caused by genetic factors and increased androgen activity, leading to hair follicle miniaturization.

A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

CD34+ and CD34- melanocyte stem cells have different regenerative abilities.

Epithelial stem cells can adapt and help in tissue repair and regeneration.

iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.

Turning off the Lhx2 gene in mouse embryos leads to slower wound healing and scars.

Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.

Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.

SP1 promotes and KROX20 inhibits hair cell growth by affecting the CUX1 gene.