Male Pattern Baldness: Psychological Impact, Disease Association, and Treatment Options

    July 2000 in “ Southern Medical Journal ”
    Daniel J. Hogan, MATTHEW CHAMBERLAIN
    Image of study
    TLDR Male pattern baldness is often genetic and linked to a hormone, with treatments like finasteride and minoxidil being effective for some men.
    The 2000 document reviewed male pattern baldness (MPB), or androgenetic alopecia (AGA), highlighting its psychological impact and association with diseases like coronary heart disease. It was found that AGA is likely polygenic and involves the transformation of hair follicles influenced by dihydrotestosterone (DHT). The Hamilton-Norwood scale is used for classifying AGA severity. Treatment options include finasteride and minoxidil, which have shown some effectiveness. Specifically, a study showed that 1 mg of finasteride daily resulted in a significant increase in scalp hair count in 66% of men after 24 months, and 42% showed visible regrowth in the anterior mid-scalp area. Biopsy results indicated a reversal of hair miniaturization. However, finasteride was not effective for postmenopausal women. Combination therapy with finasteride and minoxidil showed improvement in one case from MPB Hamilton stage V to stage III in 12 months. The document concludes that while these therapies offer hope, results vary and take time, with new treatments targeting different enzymes and receptors under investigation.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Having androgen receptor density and sensitivity at wrong f*ing place

      in Satire  7 upvotes 2 months ago
      The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

      community A Different Take on Curing MBP

       16 upvotes 5 years ago
      Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.

      community Why is dht bad for scalp hair but good for hair on the rest of body?

      in Satire  109 upvotes 1 year ago
      The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

    Similar Research

    5 / 1000+ results