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This study found that injectable gelatin/metal/tea polyphenol double nanonetworks significantly accelerated wound healing in diabetic wounds by enhancing cell migration and providing anti-inflammatory and antioxidant properties, without detectable cytotoxicity in tests.

This study reviews various skin models and methodologies used to assess the follicular penetration of nanoparticle-based drugs, highlighting inconsistencies that complicate comparisons and aims to establish more uniform protocols for clearer study outcomes.

This review highlights the inadequacy of the "specificity paradigm" in drug design for complex diseases like Alzheimer's and cancer, suggesting a shift toward developing multitarget drugs to improve treatment efficacy by interacting with multiple targets through various mechanisms.

This study introduced a new spectrofluorometric method using a synthesized organic fluorophore to effectively analyze darolutamide and thalidomide in pharmaceutical preparations and biofluids.

This study concluded that the liquid chromatography-mass spectrometry method developed is viable for accurately quantifying spironolactone and its metabolite canrenone in plasma despite interference from plasma components.

This study reported that clozapine and its metabolite showed a preference for binding to pigmented hair, but were also detectable in non-pigmented hair of patients with Parkinson's, with high correlations between dose and hair concentration.

This review highlights recent advancements in microfluidics for 3D tissue model generation and discusses its applications in tissue engineering and high-throughput drug screening without reporting new experimental results.

This review discusses using human follicular fluid in metabolomic analysis as a diagnostic tool and predictor of success in assisted reproductive technology for PCOS patients, reporting no new results.

This review discusses how extracellular vesicles play a dual role in age-related diseases by contributing to both disease pathogenesis and potential therapeutic strategies through the transfer of specific molecules.

This study found that biliverdin beta and delta, metabolites of heme, play a critical role in Pseudomonas aeruginosa iron acquisition and cooperative behaviors, which are crucial for the bacterium's long-term infection in cystic fibrosis patients, suggesting potential targets for new therapies.

This study developed and validated a highly sensitive method using ultrahigh-performance liquid chromatography with tandem mass spectrometry for accurately analyzing nine neuroactive steroids in human serum, which could enhance understanding of disease pathophysiology and support new biomarker and therapeutic discovery.

This review discusses recent advancements in the assembly and potential applications of gold nanoclusters, but presents no new experimental results; the authors highlight the need for further exploration in this area.

In this review, researchers introduced clinically tunable siRNA delivery systems for hair loss treatment, discussing design principles and analyzing relevant clinical trials to propose a framework for optimizing siRNA delivery in a clinical context.

This study evaluated two bimatoprost 1% formulations for androgenetic alopecia in men, finding both formulations achieved effective drug concentrations in the scalp with no significant differences between them, and were well tolerated over the 14-day application period.

This review outlines the design and engineering of multifunctional hydrogels, emphasizing their evolving biomedical applications, notably in controlled drug delivery, tissue support, and disease management, and discusses their potential for clinical translation.

This study reports the development of a natural hair-coloring system using size-controlled ink particles from cuttlefish ink combined with chitosan, achieving darker and more uniform black coloration on hair than existing plant-based natural colorants, without the need for metallic mordants.

In this study, broccoli sprout extract and sulforaphane were found to reduce cell viability, suppress growth, and induce apoptosis in breast cancer cells, and oral broccoli sprout extract inhibited tumor growth in animal models, suggesting it may be effective in managing breast cancer.

This review highlights the importance of standardizing pre-analytical procedures for collecting and extracting samples from uncommon biological specimens like breast milk and sweat in clinical metabolomics, to enhance diagnostic and biomarker discovery efforts while minimizing contamination and bias.

This study identified significant metabolic differences between volar and non-volar skin in mice, revealing distinct amino acid, sugar, and nucleotide metabolism patterns associated with skin type differentiation.

This study using high-performance liquid chromatography reported that mice with more diverse gut microbiota had higher levels of specific compounds in hair compared to those with less diversity, with stress affecting certain plasma levels.

In this study, researchers developed an LC-MS/MS method to accurately quantify cortisone and cortisol levels in human scalp hair, finding that concentrations decrease predictably along the hair shaft, which could assist in identifying abnormal glucocorticoid exposure.

This article reviews the role of testosterone in sexual health, supporting Testosterone Replacement Therapy as an effective treatment for Hypoactive Sexual Desire Disorder in postmenopausal women, though more research is needed on its long-term effects and applicability to premenopausal women.

This study reports that human epidermal neural crest stem cells from hair follicles can be quickly differentiated into highly pure human Schwann cells without genetic manipulation, suggesting their potential for therapeutic applications.

This study reports that a new DART-HRMS method can effectively analyze intact hair for drug use timelines, with cocaine detection aligning with forensic standards and identifying multiple drugs from high-resolution data.

In this study, the combination of arsenic toxicity and hypoxia in Arabidopsis thaliana altered root development through stress-specific root growth phenotypes and changes in phosphate starvation response, energy metabolism, and redox signaling.

Isoconazole nitrate stays effective in skin and hair follicles for up to two weeks after use.

This study found that pulmonary delivery of cepharanthine significantly improved bioavailability and may provide protective effects against pulmonary fibrosis related to COVID-19 infection in a rat model.

This review discusses the use of microbial biosurfactants as a safer alternative to chemical surfactants in cosmetics due to their antibacterial, moisturizing, and low toxicity properties, but it reports no new clinical findings.

This study reviews the current research on the metabolomic profile and antimicrobial properties of the Cannabis plant, highlighting its effective antibacterial activity against multidrug-resistant bacteria while noting a lack of studies on its impact on plant and aquatic pathogens, emphasizing potential agricultural benefits.

This study concluded that dietary changes alter serum progesterone and estradiol levels in late gestation ewes, likely due to metabolism rather than changes in placental steroid synthesis.