Liquid Chromatography-Mass Spectrometry for Simultaneous Determination of Spironolactone and Canrenone in Plasma Samples

    January 2023 in “ Brazilian Journal of Pharmaceutical Sciences ”
    Ricardo Ferreira-Nunes, E.A. Almeida, Marcilio Cunha-Filho … Guilherme M. Gelfuso
    Studysummary This study concluded that the liquid chromatography-mass spectrometry method developed is viable for accurately quantifying spironolactone and its metabolite canrenone in plasma despite interference from plasma components.
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    Research cited in this study 4

    1. Follicular-Targeted Delivery of Spironolactone Provided by Polymeric Nanoparticles Colloids and surfaces. B, Biointerfaces · 2021
    2. LC-MS Bioanalytical Method for Simultaneous Determination of Latanoprost and Minoxidil in the Skin Journal of Pharmaceutical and Biomedical Analysis · 2020
    3. Follicular Delivery of Spironolactone via Nanostructured Lipid Carriers for Management of Alopecia International Journal of Nanomedicine · 2014
    4. Acne American journal of clinical dermatology · 2002