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GlossaryLiquid Chromatography-Tandem Mass Spectrometry (LC-MS)

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) is an advanced analytical technique used to identify and quantify compounds in a sample. It combines liquid chromatography, which separates the mixture into its individual components, with tandem mass spectrometry, which provides detailed information about the molecular structure and quantity of each component. This method is highly sensitive and precise, making it valuable in fields like pharmacology, biochemistry, and environmental science.

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Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations

research Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations

823 citations, February 1998 in “Analytical Chemistry”

Method detects finasteride in plasma at very low concentrations.

research LC/MS Analysis of Stratum Corneum Lipids: Ceramide Profiling and Discovery

211 citations, March 2011 in “Journal of Lipid Research”

A new, quick method was developed to analyze skin lipids, discovering a new ceramide subclass.

research A New Label-Free Screen for Steroid 5α-Reductase Inhibitors Using LC-MS

15 citations, October 2016 in “Steroids”

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

research LC-MS Bioanalytical Method for Simultaneous Determination of Latanoprost and Minoxidil in the Skin

9 citations, May 2020 in “Journal of Pharmaceutical and Biomedical Analysis”

Method measures latanoprost and minoxidil in skin accurately and precisely.

research Determination of Vitamin B3 Vitamer (Nicotinamide) and Vitamin B6 Vitamers in Human Hair Using LC-MS/MS

7 citations, July 2021 in “Molecules/Molecules online/Molecules annual”

The method can measure vitamin B3 levels in human hair accurately.

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community Interpreting pre-finisteride blood panels

in Chat 2 upvotes 1 week ago

The conversation is about someone planning to start finasteride for hair loss and wanting to interpret pre-treatment blood panels to assess the risk of side effects like gynecomastia. They list various tests to measure hormone levels and other health indicators.

community Pre-Finisteride DHT & Hormone Blood Panel

in Finasteride/Dutasteride 3 upvotes 2 weeks ago

The conversation discusses the cost and insurance coverage of a comprehensive hormone and DHT blood panel for hair loss, with a focus on finasteride treatment. The user seeks a cheaper alternative to a $700 panel recommended in a video.

community Dutasteride Isn't Working? Get a Scalp Biopsy NOW

in Finasteride/Dutasteride 19 upvotes 3 months ago

Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hair loss management.

community thoughts on this approach to topical fin that I want to try?

in Finasteride/Dutasteride 2 upvotes 9 months ago

User plans to switch from oral to .005% topical finasteride, using a solvent from minoxidilmax and later Essengen-F. They will monitor DHT levels and seek advice on solvents and sleep caps.

community Pre Finasteride Treatment, is testing for free DHT necessary?

in Finasteride/Dutasteride 6 upvotes 2 years ago

The conversation is about whether testing for free DHT is necessary before starting Finasteride for hair loss, despite having other hormone tests available. One person suggests that genetic response to DHT is more important than DHT levels and advises starting Finasteride without the free DHT test.

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