Gold Nanocluster Assemblies: Assembly Strategies and Biomedical Applications

    June 2025 in “ Nano Research
    Yufeng Sun, Ziqiang Xu, Yijing Liu, Jintao Zhu
    Studysummary This review discusses recent advancements in the assembly and potential applications of gold nanoclusters, but presents no new experimental results; the authors highlight the need for further exploration in this area.
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    The document reviews advancements in the assembly strategies of gold nanoclusters (AuNCs), focusing on self-assembly, co-assembly, and in vivo assembly and disassembly. These strategies enhance the performance of AuNCs, adding functionalities like responsiveness and targeting, which are crucial for applications in biodetection, bioimaging, and therapeutic platforms. The review highlights the potential of AuNCs in imaging and therapy, particularly for diseases such as cancer and Alzheimer's, and notes that fluorescent gold nanoclusters can inhibit hair follicle regeneration in oxidative stress environments by suppressing the NFκB signaling pathway, suggesting a potential impact on hair growth. Future developments are expected to expand the role of AuNC assemblies in various fields.
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