Gold Nanocluster Assemblies: Assembly Strategies and Biomedical Applications

The document reviews advancements in the assembly strategies of gold nanoclusters (AuNCs), focusing on self-assembly, co-assembly, and in vivo assembly and disassembly. These strategies enhance the performance of AuNCs, adding functionalities like responsiveness and targeting, which are crucial for applications in biodetection, bioimaging, and therapeutic platforms. The review highlights the potential of AuNCs in imaging and therapy, particularly for diseases such as cancer and Alzheimer's, and notes that fluorescent gold nanoclusters can inhibit hair follicle regeneration in oxidative stress environments by suppressing the NFκB signaling pathway, suggesting a potential impact on hair growth. Future developments are expected to expand the role of AuNC assemblies in various fields.