Alkyl-Terminated Gold Nanoparticles as a Self-Therapeutic Treatment for Psoriasis

October 2021 in “ Nano letters ”

Ruifang Han, Lok Wai Cola Ho, Qianqian Bai, Cecilia Ka Wing Chan, Leo Kit Cheung Lee, Paul Cheung‐Lung Choi, Chung Hang Jonathan Choi

alkyl-terminated gold nanoparticles psoriasis alkylamine polyethylene glycol PEG HAuCl4 sodium citrate NaBH4 tannic acid gold nanoparticles

TLDR Gold nanoparticles can safely and effectively treat psoriasis without drugs and have no major side effects.

The document describes the synthesis of alkyl-terminated gold nanoparticles (AuNPs) for potential use in psoriasis treatment. The synthesis process involves the conjugation of alkylamine to a bifunctional polyethylene glycol (PEG) linker, verified by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF). The document also details the creation of AuNPs of different core sizes (3 nm and 6 nm in diameter), using HAuCl4, sodium citrate, and either NaBH4 or tannic acid as reducing agents. The resultant AuNPs could potentially be used as a self-therapeutic treatment for psoriasis, although the document does not provide any experimental results or conclusions regarding their efficacy in this regard.

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