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HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.

The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.

Trichoepitheliomas can be hard to distinguish from other skin conditions and often start in teenage years.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.

The meeting highlighted major advances in skin research, including new findings on skin microbes, genetic links to skin diseases, and improved treatments for various conditions.

Finding functions for unknown GPCRs is hard but key for making new drugs.

Effective PCOS treatments require targeting specific signaling pathways.

The treatment was ineffective in humans.

Dermal stem cells help regenerate hair follicles and heal skin wounds.

Targeting ornithine decarboxylase can help prevent skin cancer.

Edar signaling is crucial for proper hair follicle development and function.

Vitamin D and its receptor may help prevent skin cancer.

Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.

Patched1 helps prevent tumors by controlling cell growth.

Vitamin D receptor helps control hair growth and could be used to treat certain skin tumors.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

Inhibiting ornithine decarboxylase may help prevent certain skin cancers.

Baby teeth stem cells can help grow hair in mice.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.

Eyelid cells share signaling components but differ in pathway activity.

Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

The CD4 protein may play a role in the behavior of certain skin cells, affecting their growth, movement, and differentiation.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

Genomic approach finds new possible treatments for hair loss.

Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.