research Assessing Dutasteride-Associated Sexual Dysfunction Using the U.S. Food and Drug Administration Adverse Event Reporting System
Dutasteride is linked to a higher chance of sexual dysfunction, especially in younger males and the elderly.
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research Nanoemulgel for Efficient Topical Delivery of Finasteride Against Androgenic Alopecia
Nanoemulgel improves hair growth and quality using finasteride without irritation.
research Modulating Testosterone Pathway: A New Strategy to Tackle Male Skin Aging?
Honokiol might help reduce male skin aging by maintaining testosterone levels.
research Combinatorial Expression of Cell Cycle Regulators Is More Suitable for Immortalization Than Oncogenic Methods in Dermal Papilla Cells
Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.
research Laser-Assisted Hair Regrowth
Fractional lasers could help hair regrowth in androgenic alopecia, but more research is needed to confirm their effectiveness and safety.
research A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels
The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.
research Pantolactams as Androgen Receptor Antagonists for the Topical Suppression of Sebum Production
Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
research The Anti-Androgen Combination, Flutamide Plus Finasteride, Paradoxically Suppressed LH and Androgen Concentrations in Pregnant Spotted Hyenas, but Not in Males
Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.
research 5α-Reductase Inhibitors: Progress and Therapeutic Potential
5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.
![Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase](/images/research/d19df8a7-8de6-4430-8a0d-4ffa1f502985/small/15608.jpg)
research Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase
New compounds were made that effectively block a specific enzyme related to androgen conditions.
research Anti-Androgen Therapy in Dermatology: A Review
Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.
research The Role of Prostaglandins in Androgenetic Alopecia
Prostaglandins may contribute to male hair loss; targeting them could help treat it.
research Effects of Non-Contingent Cocaine on 3alpha-Androstanediol: Disruption of Male Sexual Behavior
Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.
research Platelet-Rich Plasma for Hair Loss
Platelet-Rich Plasma (PRP), a protein-rich extract from a patient's blood, shows promise in improving hair density, thickness, and quality, but the best method of use and number of treatments needed for noticeable results are still unclear.
research Effect of Ethanol Extract of Plant Mixture on Hair Regeneration in Human Dermal Papilla Cells and C57BL/6J Mice
A plant mixture extract helped grow hair by boosting cell growth and growth factors while blocking a hair loss-related enzyme.
research Identification of 5α-Reductase Isoenzymes in Canine Skin
Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.
research A Dissolution Test for Finasteride in Immediate-Release Capsules
A method was developed to test the breakdown of Finasteride capsules, showing it can tell the difference between different brands and highlighting the need for standard tests and ingredient consistency.
research Platelet Rich Plasma Hybridized Adipose Transplant for the Treatment of Hair Loss: A Case Series
PHAT may improve hair growth better than PRP alone.
research Inhibition of Rab27a and Rab27b Has Opposite Effects on the Regulation of Hair Cycle and Hair Growth
Blocking Rab27a slows hair growth, while blocking Rab27b encourages it.
research Hair Growth Promotion by Extracts of Inula Helenium and Caesalpinia Sappan Bark in Patients with Androgenetic Alopecia: A Pre-Clinical Study Using Phototrichogram Analysis
Shampoo with Inula Helenium and Caesalpinia Sappan Bark extracts promotes hair growth and prevents hair loss in androgenetic alopecia patients.
research Mechanism of Androgenic Alopecia: Addressing Speculations Through Empirical Evidence
Hair loss in men is mainly caused by hormones and genes, and while current treatments can slow it down, they can't fully stop it.
research Monoclonal Antibody Against Prolactin Receptor: A Randomized Placebo-Controlled Study Evaluating Safety, Tolerability, and Pharmacokinetics of Repeated Subcutaneous Administrations in Postmenopausal Women
The drug BAY 1158061 is safe, well-tolerated, and shows potential for treating diseases related to prolactin.
research Enhanced VEGF Expression in Hair Follicle Dermal Papilla Cells by Centella Asiatica Linn
Centella asiatica extract may help promote hair growth.
research Epigallocatechin-3-Gallate Inhibits Paclitaxel-Induced Apoptosis Through the Alteration of MicroRNA Expression in Human Dermal Papilla Cells
Green tea extract helps prevent cell death and supports cell survival in hair cells exposed to a chemotherapy drug.
research Long-Term Satisfaction and Tolerability with Low-Dose Flutamide: A 20-Year Surveillance Study on 120 Hyperandrogenic Women
Low-dose flutamide improved hirsutism and satisfaction in women but had common side effects, causing some to stop treatment.
research An Ayurveda Approach to Combat Toxicity of Chemo-Radiotherapy in Cancer Patients
Ayurveda, using herbs like ginger, garlic, and turmeric, can reduce chemo-radiotherapy side effects in cancer patients.
research Caraway, Chinese Chives, and Cassia as Functional Foods Considering Nutrients and Health Benefits
Caraway, Chinese chives, and cassia may improve health and prevent diseases due to their nutrients and medicinal properties.
research Efficacy and Safety of a Novel Herbal Solution for the Treatment of Androgenetic Alopecia and Comparison with 5% Minoxidil: A Double-Blind, Randomized Controlled Trial Study
Herbal solution improves hair diameter and density more than 5% minoxidil for androgenetic alopecia.
research An Uncontrolled Case Series Using a Botanically Derived, β-Cyclodextrin Inclusion Complex in Two Androgenetic Alopecia-Affected Male Subjects
Herbal formula shows promise for hair loss treatment.
research Abstracts
The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.