Identification of 5α-Reductase Isoenzymes in Canine Skin

    July 2015 in “ Veterinary Dermatology ”
    Lucilene Bernardi de Souza, Manon Paradis, Gustavo Zamberlam … C. A. Price
    Studysummary This study identified the expression of 5αR1 and 5αR3 enzymes in canine skin, which may advance understanding and treatment of alopecia X.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on onlinelibrary.wiley.com →
    Discuss this study in the Community →

    Research cited in this study 13

    1. Deslorelin for the Treatment of Hair Cycle Arrest in Intact Male Dogs Veterinary dermatology · 2014
    2. Effect of Dutasteride 0.5 mg/day in Men with Androgenetic Alopecia Recalcitrant to Finasteride International Journal of Dermatology · 2014
    3. A Randomized, Active- and Placebo-Controlled Study of the Efficacy and Safety of Different Doses of Dutasteride Versus Placebo and Finasteride in the Treatment of Male Subjects with Androgenetic Alopecia Journal of The American Academy of Dermatology · 2014
    4. The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases Advances in Urology · 2011
    5. Perifollicular Fibrosis: Pathogenetic Role in Androgenetic Alopecia Biological & Pharmaceutical Bulletin · 2006
    6. Adrenal Steroid Hormone Concentrations in Dogs with Hair Cycle Arrest (Alopecia X) Before and During Treatment with Melatonin and Mitotane Veterinary dermatology · 2004
    7. The 5alpha-Reductase Type 1, But Not Type 2, Gene Is Expressed in Anagen Hairs Plucked from the Vertex Area of the Scalp of Hirsute Women and Normal Individuals Brazilian Journal of Medical and Biological Research · 2003
    8. Androgenetic Alopecia in Women Journal of Investigative Dermatology Symposium Proceedings · 2003
    9. Retrospective Evaluation of Sex Hormones and Steroid Hormone Intermediates in Dogs with Alopecia Veterinary Dermatology · 2003
    10. Androgens and Alopecia Molecular and Cellular Endocrinology · 2002
    11. Clinical Application of 5α-Reductase Inhibitors Journal of endocrinological investigation · 2001
    12. Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia Journal of Investigative Dermatology · 1997
    13. Species Differences in Prostatic Steroid 5α-Reductases of Rat, Dog, and Human Endocrinology · 1985