Uromedic® Pumpkin Seed Derived Δ7-Sterols, Extract and Oil Inhibit 5α-Reductases and Bind to Androgen Receptor In Vitro

    January 2018 in “ Pharmacology & pharmacy ”
    Stefan Heim, Stephanie Seibt, Heike Stier, Margret I. Moré
    Studysummary This study found that components derived from Uromedic® pumpkin seeds, especially Δ7-sterols, may inhibit DHT production and AR binding, potentially benefiting prostate and bladder health by moderating these mechanisms.
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    Research cited in this study 2

    1. Evaluation of 5α-Reductase Inhibitory Activity of Certain Herbs Useful as Antiandrogens Andrologia · 2013
    2. The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases Advances in Urology · 2011