Nanoemulgel for Efficient Topical Delivery of Finasteride Against Androgenic Alopecia

August 2020 in “ Journal of Pharmaceutical Innovation ”

Deepak Upadhyay, Amit Sharma, Navjot Kaur, G. D. Gupta, Raj Kumar Narang, Vineet Kumar

finasteride nanoemulgel androgenic alopecia topical delivery hair growth Propecia

TLDR Nanoemulgel improves hair growth and quality using finasteride without irritation.

The study developed a stable and efficacious topical delivery system for finasteride against androgenic alopecia. The researchers prepared a finasteride-loaded nanoemulgel that showed a higher degree of hair growth in terms of hair diameter, length, and quality. The gel was also observed to be non-irritant on topical administration. The results suggest that the finasteride-loaded nanoemulgel is a stable and efficacious option for topical delivery of finasteride against androgenic alopecia.

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Research cited in this study

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research Mechanism of Androgenic Alopecia: Addressing Speculations Through Empirical Evidence

3 citations, October 2019 in “Dermatologic Therapy”

Hair loss in men is mainly caused by hormones and genes, and while current treatments can slow it down, they can't fully stop it.

research Design of Finasteride-Loaded Nanoparticles for Potential Treatment of Alopecia

48 citations, January 2017 in “Skin Pharmacology and Physiology”

Finasteride-loaded nanoparticles may help treat alopecia.

research Drug Discovery for Alopecia: Gone Today, Hair Tomorrow

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Topical drugs and near-infrared light therapy show potential for treating alopecia.

research Female Pattern Hair Loss: A Review Article

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Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.

research The Role of Androgen and Androgen Receptor in Skin-Related Disorders

124 citations, July 2012 in “Archives of Dermatological Research”

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

research Finasteride and Sexual Side Effects

39 citations, January 2012 in “Indian Dermatology Online Journal”

Finasteride may cause sexual side effects like erectile dysfunction, but they are reversible and affect less than 2% of men.

research Effect of Citrullus Colocynthis Schrad Fruits on Testosterone-Induced Alopecia

31 citations, September 2009 in “Natural Product Research”

Citrullus colocynthis fruit extract may effectively treat testosterone-related hair loss, similar to finasteride.

research Use of Finasteride in the Treatment of Men With Androgenetic Alopecia

38 citations, June 2003 in “Journal of Investigative Dermatology Symposium Proceedings”

Finasteride effectively improves hair growth and slows hair loss in men with male pattern baldness.

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