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PRP is a safe natural treatment that improves skin by reducing wrinkles and enhancing texture for up to 4 months.

This study found that platelet-rich plasma injections followed by mesotherapy improved hair count and thickness in alopecia patients, with no significant side effects reported.

This study introduced a novel scarless healing material called pgPE, made from a porous UHMWPE nanomembrane, and found that it promotes complete skin reconstruction and hair follicle regeneration by alleviating hypoxia and modulating immune responses to foster scar-free wound healing.

Keratinocyte growth factor significantly alters skin and tissue development.

This study suggests that the GDNF signaling pathway may enhance skin regeneration, as observed in axolotls and Spiny mice, indicating potential for similar processes in humans.

This study suggests that nerve growth factor may support hair follicle growth in Liaoning cashmere goats through pathways involving its receptor, TrkA, particularly during the anagen phase.

In this study, researchers found that the evolutionary and structural features of the oFGF5 gene in sheep may influence hair follicle development and hair growth regulation.

This study found that GDNF promotes hair formation and skin wound repair by enhancing the self-renewal and differentiation of bulge stem cells in mice.

This study identified FP-1 as a highly specific extracellular matrix protein in follicular papilla cells, which may play a role in hair growth regulation during specific hair cycle phases.

This review discusses the use, efficiency, and preparation methods of autologous platelet concentrates in wound healing and periodontal regeneration, but it reports no new clinical findings.

This study found that corticotropin-releasing factor influences cytokine expression related to hair growth in human dermal papilla cells and suggests CRF receptor antagonists could be potential treatments for stress-induced hair loss.

PRSS35 enzyme may help start skin tumors and could be a target for cancer treatment.

This review analyzes Platelet-Rich Plasma therapy for facial aesthetics, discussing its principles, efficacy, safety, and future research directions, but reports no new clinical results.

This study found that endogenous EGF may play a role in epidermal development and wound healing, while the absence of bFGF in embryonic rats' skin could contribute to non-scar healing.

This study found that combining PRP with concentrated growth factors was more effective than PRP alone in promoting hair regrowth for patients with androgenetic alopecia.

This review highlights the positive effects of platelet-rich plasma in aesthetic and regenerative medicine, particularly for skin rejuvenation, anti-aging, hair reconstruction, and wound healing, but it reports no new clinical results.

This letter comments on a randomized controlled trial by Shapiro et al that found no significant benefits of platelet-rich plasma compared to placebo for male androgenetic alopecia, highlighting issues with PRP protocol variations.

This review suggests that injectable platelet-rich fibrin therapy shows promise for improving hair density in androgenetic alopecia and enhancing facial skin texture and elasticity, but larger studies are needed to confirm its effectiveness.

In this case study, a 29-year-old woman with Pseudopelade of Brocq, a type of scarring alopecia, showed significant hair density improvement following a combination of scalp reduction surgery and concentrated growth factor injections postoperatively, which addressed scar complications and inflammation.

This review discusses recent research on the use of concentrated growth factor (CGF) for treating androgenetic alopecia, highlighting its potential to enhance hair regrowth and improve hair density but noting the need for high-quality clinical trials.

This study suggests that phloroglucinol may enhance anagen signaling and reduce oxidative stress-induced damage in human dermal papilla cells, offering a potential therapy for hair loss.

This study demonstrates that the amino-terminally shortened KGF-1 variant with 135 residues maintains biological activity, suggesting it may serve as an alternative to the original KGF-1 for certain therapeutic applications.

This study found that altering levels of SFRP1 in human dermal papilla cells affects cell function and regulates Wnt/β-catenin signaling or telomerase activity, suggesting that targeting SFRP1 could potentially offer a new approach to treat hair loss diseases.

This study found that a standardized PRP application protocol was effective as a coadjuvant therapy in most patients with androgenetic alopecia who did not respond to minoxidil or finasteride, based on improvements in Ebling's scale.

This study constructed a hair follicle-specific expression vector for IGFBP-5 in Inner Mongolia Cashmere goat cells, allowing for future functional genetic analyses and potential use in nuclear transfer.

This study identified ISPP-Rb, a novel immuno-stimulatory complex from Royoporus badius, that significantly activates murine macrophage cells and induces multiple proinflammatory cytokines.

The researchers reported that freeze-dried collagen-activated platelet-rich plasma increased transforming growth factor-β1 levels compared to non freeze-dried PRP with collagen, suggesting a potential benefit for tissue regeneration.

This study reported that in patients with androgenic alopecia, platelet-rich plasma therapy's effectiveness in enhancing hair density and caliber was positively correlated with specific growth factor concentrations, notably glial cell-derived neurotrophic factor and platelet-derived growth factor-BB, while no significant correlations were found with demographic factors.

In this in vitro study, simple centrifugation with calcium gluconate activation led to a significantly higher release of PDGF-BB in PRP compared to other methods, which may inform improved clinical PRP preparation protocols.

In this study, researchers demonstrated that treating platelet rich plasma with microsecond pulsed electric fields effectively activates platelets and induces similar or higher growth factor release compared to traditional bovine thrombin, suggesting a potential clinical use that may be more cost-effective and practical.