Production of a 135-Residue Long N-Truncated Human Keratinocyte Growth Factor 1 in Escherichia Coli

    May 2022 in “ Research Square (Research Square) ”
    Young Su Kim, Hye‐Jeong Lee, Gabriella Aphrodita Handoko … Jungoh Ahn

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary This study demonstrates that the amino-terminally shortened KGF-1 variant with 135 residues maintains biological activity, suggesting it may serve as an alternative to the original KGF-1 for certain therapeutic applications.
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    Research cited in this study 4

    1. Functional Hair Follicle Regeneration: An Updated Review Signal Transduction and Targeted Therapy · 2021
    2. Maintaining Hair Inductivity in Human Dermal Papilla Cells: A Review of Effective Methods Skin Pharmacology and Physiology · 2020
    3. FGF Family: From Drug Development to Clinical Application International Journal of Molecular Sciences · 2018
    4. KGF And EGF Signaling Block Hair Follicle Induction And Promote Interfollicular Epidermal Fate In Developing Mouse Skin Development · 2009

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