November 2023 in “Periodontology 2000” This narrative review examines the technological advancements and clinical applications of liquid injectable platelet-rich fibrin (i-PRF), discussing its use across regenerative periodontology, sports medicine, and more, as well as its potential as a drug delivery system.
64 citations
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March 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This study describes GPRC5D's unique expression pattern in tissues that produce hard keratin, with retinoic acid inducing its expression in hair bulb cells and affecting keratin gene regulation.
January 2024 in “Journal Of Advanced Zoology” This review examines platelet-rich plasma for tissue repair and regeneration, reporting promising but inconclusive efficacy across applications; the authors stress the need for rigorous clinical trials.
January 2023 in “The Egyptian Journal of Hospital Medicine” This review suggests that platelet-rich plasma therapy may be an effective treatment for androgenetic alopecia, with low downtime and minimal adverse effects reported in the studies analyzed.
January 2023 in “Journal of Cosmetic Dermatology” This review concludes that platelet-rich plasma treatment is effective for androgenetic alopecia, with recommendations for a specific volume, frequency, and duration of therapy for optimal results.
75 citations
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September 2016 in “EMBO journal” This study found that PRC2 plays a crucial role in maintaining intestinal homeostasis by supporting progenitor cell proliferation and limiting secretory lineage differentiation.
February 2025 in “Archives of Dermatological Research” In this study, researchers administered injectable platelet-rich fibrin (i-PRF) to 30 patients with androgenetic alopecia, finding an 80% response rate after 6 months, with improved hair density and reduced scalp symptoms, while reporting minimal adverse reactions.
April 2017 in “Plastic surgical nursing” Platelet-rich plasma (PRP) is an effective treatment for hair loss that involves scalp injections and requires ongoing maintenance.
This review outlines platelet-rich plasma practices for androgenetic alopecia at a large academic center and highlights the importance of standardizing PRP protocols to improve treatment outcomes, but it reports no new clinical results.
November 2018 in “Biomedical Journal of Scientific and Technical Research” This article discusses the use of PRP and long-acting PRP for treating Female Pattern Hair Loss, emphasizing their potential benefits, but reports no new clinical results.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that platelet-rich plasma therapy may improve hair density and thickness in androgenetic alopecia, especially in early to moderate stages, though standardization of preparation is needed for consistent results.
This article reports that PRP therapy shows promise as a safe and effective non-surgical treatment for hair loss, suitable for those with early to moderate androgenetic alopecia.
January 2022 in “Springer eBooks” This review discusses platelet-rich plasma therapy for hair restoration and reports no new clinical results.
19 citations
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August 2019 in “Seminars in Plastic Surgery” This review explains the biology and preparation of platelet-rich plasma and discusses its clinical applications in plastic surgery, but reports no new findings.
January 2026 in “Andrology” This study found that PRP injections are safe and may slightly reduce penile curvature and improve PDQ scores in men with stable-phase Peyronie's Disease, but the changes are not significant enough to predict long-term effects.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This article discusses the popularity and mechanisms of Platelet Rich Plasma therapy for skin rejuvenation and hair loss, but it reports no new clinical results.
February 2022 in “Cosmetic Dermatology” This article reviews the role of Platelet Rich Plasma in cosmetic dermatology and discusses a new method for storing PRP for personalized home use without reporting clinical outcomes.
14 citations
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March 2019 in “Journal of Cosmetic Dermatology” This laboratory study found that activated platelet‐rich plasma supernatant enhanced hair growth signaling pathways in cultured human dermal papilla cells, suggesting potential for treating androgenic alopecia.
5 citations
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December 2018 in “Journal of Cosmetic Dermatology” This study found that after treatment with platelet-rich plasma, male androgenetic alopecia patients showed significant improvements in hair count, hair diversity, and reduction in certain dermoscopic features.
In this observational and interventional study conducted in Dhaka, Bangladesh, PRP treatment led to clinical improvements in hair count, thickness, and density among 20 out of 30 male patients with androgenetic alopecia, with significant statistical support (p-value 0.00) following 2-3 treatment sessions.
12 citations
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June 2019 in “Psychoneuroendocrinology” This study found that in rodent models, the ability of D1 dopamine receptor activation to impair sensory gating is facilitated by 5α-reductase type 1, which produces allopregnanolone.
April 2019 in “Journal of Investigative Dermatology” In this pilot study, combined platelet-rich plasma therapies showed potential benefits for improving skin elasticity and vascular network density in morphea patients, but the small sample size limits definitive conclusions.
October 2025 in “Infection Control and Hospital Epidemiology” This article discusses developing a standardized operating procedure for PRP administration to align with infection prevention regulatory standards and reports no new clinical results.
October 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” This study evaluated the effects of platelet-rich plasma (PRP) on endometriosis but found no statistically significant overall difference in endometriotic foci size reduction between treated and control groups.
27 citations
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July 2017 in “Facial Plastic Surgery” This review examines the growing evidence for using platelet-rich plasma in aesthetic procedures such as hair restoration and skin rejuvenation but reports no new clinical results.
3 citations
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October 2020 in “Journal of Transfusion Medicine” This review discusses the use and mechanisms of platelet-rich plasma therapy and highlights the need for standardized preparation and application protocols, without reporting new clinical results.
12 citations
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March 2023 in “The FASEB Journal” This study found that platelet-rich plasma treatment significantly improved erectile function and restored neural structures in aged rats with erectile dysfunction, suggesting potential benefits for geriatric patients.
April 2023 in “Journal of Investigative Dermatology” This study found that sebaceous glands can regenerate after PPARg deletion in adult skin, relying on the hair cycle and FGFR signaling.
1 citations
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April 2019 in “Advances in Cosmetic Surgery” Platelet-rich plasma shows potential for hair growth, but more research is needed to determine the best preparation method.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study from PRP Bristol suggests that PRP therapy may stimulate hair growth by revitalizing dormant follicles, noting its rising popularity as a non-surgical option for hair restoration.