Trimodal Minimally Invasive Therapy for Stable-Phase Peyronie's Disease: A Two-Center Real-Life Prospective Pilot Study

    January 2026 in “ Andrology
    F Negri, E. Pozzi, Leutrim Zahiti, Gabriele Birolini, Massimiliano Raffo, Alessia Dr. D'arma, Francesco Montorsi, Agostino Mattei, Andrea Salonia
    TLDR PRP injections are safe but don't significantly improve Peyronie's Disease.
    The study investigates the safety and efficacy of PRP injections for men with stable-phase Peyronie's Disease (PD). Results indicate that PRP injections are safe and may lead to modest improvements in penile curvature and PDQ scores. However, the reduction in curvature observed is not significant enough to suggest meaningful long-term clinical outcomes. The study concludes that larger controlled studies are necessary to better understand the potential benefits of this treatment.
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