The Effects of Leukocyte- and Platelet-Rich Plasma (L-PRP) and Pure Platelet-Rich Plasma (P-PRP) on a Rat Endometriosis Model

The study investigated the effects of leukocyte- and platelet-rich plasma (L-PRP) and pure platelet-rich plasma (P-PRP) on endometriosis in a rat model. Endometriosis foci were created and treated with saline, L-PRP, or P-PRP. Results showed that while there was a significant reduction in implant volumes within each group by the end of the experiment, there was no statistically significant difference between the groups in terms of volume reduction or histopathological and immunohistochemical assessments. Both L-PRP and P-PRP led to more reduction in endometriosis foci, but without statistical significance compared to the control.