The Effects of Leukocyte- and Platelet-Rich Plasma (L-PRP) and Pure Platelet-Rich Plasma (P-PRP) on a Rat Endometriosis Model

    October 2019 in “ bioRxiv (Cold Spring Harbor Laboratory) ”
    Ali Doğukan Anğın, İsmet Gün, Önder Sakin, Muzaffer Seyhan Çıkman, Zehra Meltem Pirioğlu, Ahmet Kale, Kayhan Başak, Pınar Kaygın, Serpil Oğuztüzün
    TLDR L-PRP and P-PRP reduced endometriosis in rats, but not significantly more than saline.
    The study aimed to investigate the effects of platelet-rich plasma (PRP) derivatives on endometriosis using a rat model. It involved 33 rats divided into groups receiving saline, leukocyte- and platelet-rich plasma (L-PRP), and pure platelet-rich plasma (P-PRP). The results showed that while there was a significant reduction in the volume of endometriotic foci within each group by the end of the experiment, there was no statistically significant difference between the groups in terms of volume reduction or histopathological and immunohistochemical assessments. Although L-PRP and P-PRP led to more reduction in endometriosis foci, they did not result in statistically significant differences compared to the control.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 108 results

      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 1 year ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community Platelet rich plasma treatment

      in Treatment  6 upvotes 1 year ago
      A 27-year-old male experienced rapid hair loss after dengue fever, which activated a balding gene. The doctor suggested platelet-rich plasma treatment for hair regrowth.

      community platelet rich plasma experiences/thoughts?

      in Treatment  3 upvotes 3 years ago
      Hair loss discussion includes treatments like Minoxidil, finasteride, and RU58841. Platelet rich plasma treatment is considered expensive but cheaper than hair transplant.

      community PRP ( PLATELET-RICH-PlASMA) for hair loss

      in Treatment  1 upvotes 2 years ago
      A 27-year-old male experiencing hair loss post-Covid is considering PRP (platelet-rich plasma) therapy. He's seeking personal experiences about the process, particularly regarding pain levels, despite his dermatologist's assurance of using local anesthesia.

      community Do Platelet-rich plasma, PRP work?

      in Research/Science  13 upvotes 2 years ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

    Similar Research

    6 / 1000+ results