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This study describes a novel hairless mutant rat strain, F344-Hr(krh), developed via ENU mutagenesis, which provides a model for skin disease and potentially focal glomerulosclerosis due to specific genetic mutations.

In this study, rapamycin was found to increase hair follicle pigmentation and prolong anagen duration in cultured human scalp hair follicles, suggesting it could be explored as an anti-greying agent.

This review examines the growing evidence for using platelet-rich plasma in aesthetic procedures such as hair restoration and skin rejuvenation but reports no new clinical results.

This review suggests that injectable platelet-rich fibrin therapy shows promise for improving hair density in androgenetic alopecia and enhancing facial skin texture and elasticity, but larger studies are needed to confirm its effectiveness.

This study reported that exposure to 1,763 MHz radiofrequency radiation stimulated hair growth in vitro by inducing insulin-like growth factor-1 expression in cultured human dermal papilla cells.

In this split-scalp study, researchers observed that combining fractional CO2 laser and PRP treatment was significantly more effective in improving hair parameters in women with female pattern hair loss than using each intervention alone or placebo.

This case report describes how personalized treatment based on Encyclopedic Tumor Analysis successfully led to durable regression in a woman with advanced pilomatrical carcinoma, unresponsive to standard care.

This study found that knocking down SFRP2 in an AGA model improved hair regeneration and reduced cellular dysfunction, suggesting that targeting the SFRP2-FSTL1 axis could be a promising therapeutic strategy for androgenetic alopecia.

This review discusses recent clinical trials on the use of platelet rich plasma for treating androgenetic alopecia and reports mixed findings on its effectiveness compared to standard treatments.

This review discusses recent advancements in platelet-rich plasma therapies for tissue repair and regenerative medicine, but reports no new clinical results, highlighting a need for translating research into human clinical protocols.

This study found that local heterologous leukocyte-rich platelet-rich plasma improved distal skin flap viability in rats by reducing necrosis compared to the control group.

This study found that a single session of nanofat combined with platelet-rich plasma significantly increased hair density and thickness in male androgenic alopecia patients compared to platelet-rich plasma alone, with effects partially persisting at 12 months.

This study established a stable cell line for CRF1 receptor screening, which can be used to develop functional cosmetics and modulators potentially affecting hair re-growth.

This study identified a 290 Kb microduplication in chromosome 1q22 in a family with members exhibiting neurodevelopmental disorders, suggesting a link between this genetic alteration and the observed neurological symptoms.

This study found a severe MBTPS2 gene mutation in a Japanese IFAP syndrome patient, suggesting other factors may influence the syndrome's clinical features compared to previously studied patients.

This review discusses the role of platelet-rich plasma therapy in various cosmetic procedures, finding potential benefits in improving tissue homeostasis if harvesting standards are maintained, but reports no new clinical results.

In a dermal Gorab knockout mouse model, this study found that Gorab mutations increase P53 protein accumulation and disrupt extracellular matrix expression, contributing to accelerated skin aging and suggesting a pathway involving epigenetic regulation.

In this study using a mouse model, researchers found that expressing Lef1 in dermal fibroblasts may enhance skin regeneration without affecting normal development.

This study observed that Trps1 gene expression in mice is precisely regulated in skin development, particularly during hair follicle morphogenesis, with distinct localization patterns in different cell types.

This book chapter reviews the subclasses and applications of platelet-rich plasma in tissue engineering and highlights the challenges in clinical translation without reporting new clinical results.

This study suggests that PDRN may enhance wound healing by reducing MIR135b expression, which in turn increases FOXO1 expression in keratinocytes.

This study suggests that FGF18 may enhance radioresistance in telogen hair follicles by inducing cell cycle arrest, potentially serving as a radioprotector against radiation-induced hair follicle damage.

This study reported a drug-induced pityriasis rubra pilaris-like eruption in a patient treated with sorafenib, suggesting a possible effect of sorafenib on keratinocyte biology.

This study found that proretinal nanoparticles, applied topically, are safe and effective for penetration into hair follicles, enhancing retinoid biological activity in the skin while reducing irritation compared to conventional retinal formulations.

This study found that serine 44 in the N-terminal head domain of keratin 17 is phosphorylated in response to various stimuli affecting skin keratinocyte growth, linking K17 up-regulation with growth and stress responses in skin epithelium.

This study found that men without prostate cancer carrying the A-allele of SNP rs1204038 had a 65% higher risk of PSA levels above 3 ng/mL compared to those with the G-allele, increasing referrals for further examination.

The researchers reported that targeting glycoprotein 130's signaling site in animal models promoted tissue regeneration and reduced osteoarthritis progression through anti-inflammatory and protective effects.

The researchers reported that both finasteride and PM-9 competitively inhibit the 5 alpha-reductase enzyme in P. crustosum broth.

This study found that Puerariae Radix ethanol extracts increased the proliferation of human hair dermal papilla cells via ERK and Akt phosphorylation, suggesting potential benefits for alopecia treatment.

This study found that those with pityriasis rubra pilaris reported worse quality of life than patients with most other dermatologic conditions, impacting daily activities and emphasizing its severe life quality implications.