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This review examines quality control in preparing platelet-rich plasma, highlighting knowledge gaps in its clinical efficacy and safety, but reports no new clinical results.

Reduced TRPS1 leads to increased STAT3 and SOX9 in hair follicles, affecting hair growth.

In this study, a single platelet-rich plasma injection for facial rejuvenation improved patient satisfaction and skin elasticity, with the most notable effects occurring 1-2 weeks post-treatment.

Deleting Crif1 in mouse skin disrupts skin balance and hair growth.

This study found that injecting PRP gel derived from a patient's own blood may promote tissue regeneration and closure of intestinal fistulas unresponsive to conservative therapy.

In this study, researchers identified a novel p.R50X mutation in the vitamin D receptor gene, linked to hereditary vitamin D-resistant rickets in two siblings.

This study in a nine-year-old boy from Lebanon identified a gene mutation (c.1066dup p.(Arg356Profs*16)) associated with a rare inborn error of immunity, characterized by craniosynostosis, jaundice, and several other symptoms, expanding the known genotypic and phenotypic spectrum of this condition.

The Celsr1 gene is crucial for normal hair patterning in mice.

This review discusses the mechanisms and potential benefits of platelet-rich plasma therapy for various skin conditions and reports no new clinical findings.

This study reviewed preliminary evidence suggesting platelet-rich plasma could play a significant role in hair restoration, with animal experiments showing faster hair cycle transitions compared to controls.

This study found that Rac1 activity in specific skin compartments is sufficient for hair formation, but results in hair with altered structure and pigmentation compared to normal.

In this study, researchers found that the protein eIF4E is crucial for keratinocyte proliferation in psoriasis, suggesting it as a potential treatment target for the condition.

Progranulin overexpression leads to shorter, thinner hair and increased cell death in mouse hair follicles.

This study found that Foxp1, a transcriptional factor, plays a key role in regulating hair follicle stem cell proliferation by modulating oxidative stress and the cell cycle during hair growth phases.

This study found that a newly produced version of KGF-1 with 135 residues maintained biological activity and could serve as an alternative to the standard 140-residue KGF-1.

This study found that mitochondrial dysfunction due to Crif1 deficiency in hair follicle stem cells significantly slows the hair growth cycle in adult mice but does not impact the maintenance of HFSC populations.

This review summarizes current clinical evidence on platelet-rich plasma, highlighting its effectiveness in treating androgenetic alopecia and as an adjunctive therapy for acne scars, while noting challenges in standardizing preparation techniques.

In this study, researchers examined a patient with ZMYM2::FGFR1 fusion-positive leukemia, finding that Pemigatinib showed efficacy, while Ponatinib resistance was linked to a specific FGFR1 mutation. Other FGFR inhibitors demonstrated high effectiveness in ex vivo assays.

In this study, researchers discovered that fat grafting helps reduce dermal fibrosis in radiation-injured mouse skin by decreasing specific fibroblast subpopulations associated with Fra/c-Jun signaling.

This research observed that removing RNase L in mice enhances regenerative capacity through increased IL-36 and wound-induced hair neogenesis, highlighting RNase L as a gene that represses regeneration by moderating immune responses during viral infections.

This study found that intraovarian PRP treatment in women with low ovarian reserve was associated with significant increases in serum AMH levels in some patients, typically within four weeks.

In this study involving 15 women with alopecia, subcutaneous scalp injections of platelet-rich plasma every four weeks for three sessions led to increased hair and hair follicle density at 24 weeks, with common side effects being local swelling and pain.

This study found that among male Han Chinese, a higher polygenic risk score was linked to increased risk and poorer treatment outcomes for benign prostatic hyperplasia.

This bibliometric analysis reported that PRP is most frequently studied for hair restoration, especially in placebo-controlled trials, although differences in PRP preparation and outcome measures challenge result consistency across studies.

This review discusses platelet-rich plasma therapy for hair restoration and reports no new clinical results.

In this study, researchers found that certain cytokines can significantly down-regulate PDGF expression in dermal papilla cells and follicular keratinocytes, indicating a potential link between PDGF signaling and catagen induction.

This study highlights that while platelet-rich plasma is showing promise across multiple medical fields like dentistry and sports medicine, a lack of standardized protocols and robust clinical trials limits its routine clinical application.

This paper reviews genome-based personalized medicine developments using Web services for analyzing SNPs in reproductive potential but reports no new clinical findings.

Finasteride may reduce prostate cancer risk.

More research is needed to confirm PRP's effectiveness for scarring alopecia.