Platelet-Rich Plasma for the Treatment of Postoperative Anastomotic Fistula of the Gastrointestinal Tract: A Case Report

In this study, injecting platelet-rich plasma into the muscular layer of the intestinal wall in rabbits significantly reduced adhesion development compared to soaking methods, suggesting an improvement in anastomosis regeneration.

In this study, PRP injections into the muscular layer of rabbits' intestinal walls improved anastomosis regeneration with less adhesion compared to PRP soaking, though further research is needed to determine the best application method.

This study found that injecting Platelet-Rich Plasma into the anastomotic line during low anterior resection for rectal cancer eliminated anastomotic leakage, reducing its incidence from 13.3% in the control group to 0% in the PRP group.

This study found that using autologous adipose-derived stromal vascular fraction enriched with platelet-rich plasma may improve healing rates in patients undergoing flap repair for transsphincteric cryptoglandular fistulas.

This study evaluated the long-term effects of combining autologous platelet-rich stroma injection with transanal advancement flap repair for cryptoglandular transsphincteric fistulas and found that it resulted in primary clinical closure and radiological healing in a high percentage of patients, with low recurrence rates.