Nanofat and PRP vs PRP in Androgenic Alopecia: An Intra-Patient Case-Control Study

    Michelangelo Vestita, Domenico Bonamonte, Francesco Ciancio, Rosario Emanuele Perrotta, Eleonora Nacchiero, Giuseppe Giudice
    From the encyclopedia
    Platelet-Rich Plasma →

    growth factors taken from your blood and injected into your scalp to stimulate hair

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

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    Studysummary This study found that a single session of nanofat combined with platelet-rich plasma significantly increased hair density and thickness in male androgenic alopecia patients compared to platelet-rich plasma alone, with effects partially persisting at 12 months.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    In a study aimed at evaluating the efficacy and safety of combining nanofat with platelet-rich plasma (PRP) versus PRP alone in treating androgenic alopecia, 24 male patients were enrolled. The study excluded those who had received certain hair regrowth treatments in the past 6 months and required a washout period for topical minoxidil users. Each patient had a case area treated with nanofat+PRP and a control area treated with PRP only. Trichoscopy and trichogram examinations were conducted at baseline, and then at 1, 3, 6, and 12 months post-treatment by a blinded physician, along with patient satisfaction scores. Results showed a significant increase in hair density and thickness in the treated areas, with the greatest improvement at 6 months and some persistence at 12 months. No adverse events were recorded. The study concluded that a single session of nanofat+PRP provided a significant and enduring response in treating male androgenic alopecia, superior to PRP alone.
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