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AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Cavity macrophages gather on organ surfaces but don't really invade or help repair the organs after injury.

Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Overexpressing Tβ4 in goats' hair follicles increases cashmere production and hair follicle growth.

Elevated CO2 can lessen the negative impact of water shortage on soybean roots and affects specific genes.

Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

A specific microRNA, chi-miR-30b-5p, slows down the growth of hair-related cells by affecting the CaMKIIδ gene in cashmere goats.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.

Dermal EZH2 controls skin cell development and hair growth in mice.

Notch1 signaling is crucial for improving wound healing and skin regeneration by affecting stem cell behavior.

MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.

Researchers identified genes in scalp hair follicles that may affect hair traits and hair loss.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.

A protein called FERONIA helps control root hair growth in response to cold and low nitrogen by activating nutrient-sensing pathways in a plant called Arabidopsis.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

The PTGER2 gene is highly active in Cashmere goat skin and its activity changes with the hair growth cycle.

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.

Different light affects cell functions and can help treat skin conditions.

Hair follicle stem cells help skin heal and grow during stretching.