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Mutations in iRhom2 affect hair and skin in mice and are linked to esophageal cancer, with ADAM17 playing a crucial role.

Gray hair can potentially be reversed, leading to new treatments.

Effective PCOS treatments require targeting specific signaling pathways.

Shi-Bi-Man activates hair follicle stem cells and promotes hair growth by changing lactic acid metabolism and other cellular processes.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Psoriasis may be chronic because it lacks certain immune system controls that prevent overreaction.

New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.

Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

Protein tyrosine kinases are key in male pattern baldness, affecting skin structure, hair growth, and immune responses.

Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Certain genetic variations in the FST gene are linked to better wool quality in Chinese Merino sheep.

OCT4 helps granulosa cell growth in early-stage follicles, and FSH increases OCT4 through specific pathways.

Centella asiatica extract may help promote hair growth by blocking a specific cell signaling pathway.

DNA methylation likely doesn't cause different lambskin patterns in Hu sheep.

Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.

SOX9 is essential for the development of various organs and hair follicles.

The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.

Certain immune cells worsen post-surgery gut paralysis by activating a specific immune response.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

Botryococcus terribilis Ethanol Extract may reduce inflammation by changing gene expression in cells.

A specific genetic change in the KRT71 gene causes a hair loss condition in Hereford cattle.

Azelaic acid helps protect hair cells from UV damage and encourages hair growth by increasing certain gene expressions and proteins.