October 2025 in “International Journal of Cosmetic Science” This study found that longer-chain cationic surfactants like BTMC provided superior hair conditioning by reducing combing forces, but did not reverse oxidative hair damage, emphasizing the role of molecular structure in surfactant performance.
January 2024 in “World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany” Polisorbate 20 is not suitable for curl creams due to instability.
May 2024 in “Nano letters” This study developed a quercetin-encapsulated and polydopamine-integrated nanosystem that reshapes the perifollicular microenvironment, showing potential for rescuing hair follicle viability and regenerating hair follicles in androgenic alopecia by scavenging reactive oxygen species and promoting angiogenesis.
September 2022 in “Journal of pharmaceutical sciences” This study found that adding hydroxypropyl cellulose to minoxidil formulations significantly increased scalp retention and penetration compared to other formulations, potentially leading to reduced application frequency and improved efficacy.
16 citations
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January 2023 in “Acta Biomaterialia” This study reported that a new bioinspired injectable hydrogel, CQCS@gel, showed promise as a multifunctional wound dressing by achieving rapid hemostasis and promoting the healing of infected skin wounds in both in vitro and in vivo tests.
July 2022 in “Institutional Repositories DataBase (IRDB)” 3D spheroid cells effectively test hair growth compounds like Minoxidil.
9 citations
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July 2015 in “Clinical Cosmetic and Investigational Dermatology” This study found that QV Face Rescue Gel effectively induces collagen production, reduces UV-induced erythema, and decreases transepidermal water loss on sensitive facial skin, while being nonstinging, nonirritating, and noncomedogenic.
2 citations
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January 2014 in “Sen i Gakkaishi” This study verified that a new straightening process involving a flat iron, ammonium thioglycolate, and hydrogen peroxide may permanently straighten wavy hair by eliminating disulfide bond distortions.
9 citations
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September 2018 in “Journal of Photochemistry and Photobiology B-biology” This study demonstrated that combining l-cystine and thiamin in a formulation may protect against UV-induced damage in growth-limited human epidermal keratinocytes in vitro.
November 2023 in “Regenerative Biomaterials” This study developed a degradable and bioactive citrate-based polyurethane adhesive that achieves rapid and strong tissue adhesion, exhibiting improved bonding strength in wet environments, biocompatibility, biodegradability, and hemostatic properties, with potential to enhance wound healing by promoting angiogenesis.
1 citations
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December 2016 in “Vìsnik farmacìï” This study found that a gel base with 0.2% potassium sorbate, 5% glycerin, and other specified components has optimal properties for use in telogen effluvium treatments.
July 2025 in “Journal of Investigative Dermatology” TRIV-509 quickly improves skin barrier and cell health in atopic dermatitis.
This article reviews the roles and types of surfactants and ingredients in modern shampoos, discussing their contributions to cleansing, conditioning, and cosmetic effects, but reports no new experimental findings.
January 2011 in “Journal of Society of Cosmetic Chemists of Japan” This study found that a conditioner containing 18-MEA and SPDA can improve hair's smoothness and reduce flyaways, enhancing hair manageability.
February 2023 in “Materials today bio” In this study, researchers developed a promising transdermal agent using Triton X-100-modified polyethyleneimine that successfully delivered genetic material to hair follicle cells in mice, potentially alleviating hair loss due to androgenetic alopecia by promoting cell proliferation and inhibiting apoptosis.
January 2025 in “Biomedical Engineering Letters” This study reported that a new polymeric formulation for topical minoxidil delivery in an animal model improved hair growth and hair follicle formation more effectively than minoxidil in PBS, suggesting potential as a future hair loss treatment.
December 2025 in “Chemical Engineering Journal” This study reported that hydrogels created from keratins extracted from human hair exhibit antibacterial properties and enhance tissue regeneration, suggesting their potential use in full-thickness skin repair, as demonstrated by increased collagen production and improved healing in vivo.
July 2019 in “Ferroelectrics” The researchers reported that increasing protein content in human hair keratin/calcium alginate blend films led to larger molecular aggregates, which influenced the films' physical properties such as light transmittance and tensile strength.
April 2026 in “Cosmetics” In this randomized, double-blind, placebo-controlled trial, researchers found that a multi-targeted cosmetic formulation containing TrinogeniX™ significantly increased hair density and thickness in individuals with androgenetic alopecia without adverse effects, suggesting it as a potential safe and effective treatment option.
8 citations
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May 2020 in “International journal of biological macromolecules” In this study, researchers evaluated the binding of keratin-associated proteins and α-keratins to human hair fibers, finding that chemical preactivation significantly enhanced binding to natural hair, while perming altered binding characteristics and increased penetration depth.
12 citations
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October 2018 in “Biotechnology reports” In this study, researchers reported that the application of refolded human K31 keratin protein significantly improved diameter, mechanical strength, and smoothness of chemically damaged hair after a single treatment.
July 2019 in “Iconic Research And Engineering Journals” This study found that transparent shampoo bars containing high concentrations of aloe vera gel, castor oil, and cinnamon oil exhibited antimicrobial activity, reduced hair loss, and caused no skin irritation.
18 citations
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March 2014 in “Drug Development and Industrial Pharmacy” This study evaluated new aqueous gel formulations of minoxidil without irritants and found that the calcium alginate gel showed the best performance in terms of drug release and skin permeation.
March 2023 in “Asian journal of beauty & cosmetology” This study found that applying a keratin solution improved tensile strength, reduced absorbance, and increased gloss in damaged hair compared to untreated hair.
8 citations
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January 2009 in “Transactions of the Materials Research Society of Japan” This study found that CMAD wool keratin may protect human hair from damage during repeated bleaching and permanent waving treatments.
39 citations
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April 2010 in “International Journal of Pharmaceutics” This study found that using monoolein cubic phase nanoparticles with an entrapped hydroxypropyl β-cyclodextrin/minoxidil complex increased minoxidil skin permeation, but minoxidil retention in the skin was higher with a traditional solution.
24 citations
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November 2009 in “Pharmaceutical Development and Technology” This study found that Transcutol P significantly enhanced the skin penetration of Finasteride in vitro, while cationic and anionic surfactants did not show such effects.
2 citations
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April 2008 in “Journal of Dispersion Science and Technology” This study observed that including cationic minoxidil particles in a shampoo facilitated notable hair growth promotion despite a negative surface charge after rinsing, likely due to ionic interactions with the skin.
November 2025 in “Bioactive Materials” In this study, researchers developed a novel nucleic acid nanoparticle system incorporating quercetin, which they found enhances functional hair follicle regeneration and maintains epithelial structure stability in androgenetic alopecia by regulating hair follicle stem and dermal papilla cells.