Health Improvement of Human Hair and Their Reshaping Using Recombinant Keratin K31

October 2018 in “ Biotechnology reports ”

Abdul Basit, Faiza Asghar, Saima Sadaf, Muhammad Akhtar

recombinant keratin K31 keratin Escherichia coli hair diameter mechanical strength chemically damaged hair bleached hair curly hair hair smoothness K31 E. coli

TLDR Recombinant keratin K31 makes damaged hair thicker, stronger, and straighter.

The study investigated the effects of recombinant keratin K31 on human hair health and reshaping, finding significant improvements in hair strength, elasticity, and appearance. Recombinant keratin K31, expressed in E. coli and purified, increased hair diameter by up to 49%, doubled mechanical strength, and straightened curly hair after a single treatment. The protein's similarity to native keratin K31 allowed it to integrate into the hair structure, filling gaps and enhancing elasticity and strength, making it a promising ingredient for hair care products aimed at repairing and improving hair health.

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research An Overview of Chemical Straightening of Human Hair: Technical Aspects, Potential Risks to Hair Fiber and Health, and Legal Issues

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research The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle

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research The Human Keratins: Biology And Pathology

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research New Keratin Isolates: Actives for Natural Hair Protection

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research Hair Follicle-Specific Keratins And Their Diseases

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research Novel Type I Hair Keratins K39 And K40 Are The Last To Be Expressed In Differentiation Of The Hair: Completion Of The Human Hair Keratin Catalog

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research The Proteomics of Keratin Proteins

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research A Rapid Extraction Procedure of Human Hair Proteins and Identification of Phosphorylated Species

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research Hair Care Products: Waving, Straightening, Conditioning, and Coloring

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research Hair Care and Hair Care Products

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research Hair: Its Structure and Response to Cosmetic Preparations

86 citations , January 1996 in “Clinics in dermatology”

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