Strategies for Improved Hair Binding: Keratin Fractions and the Impact of Cationic Substructures

    May 2020 in “ International journal of biological macromolecules ”
    Randi Angela Baus, Christina Leichner, Christian Steinbring, Andreas Bernkop‐Schnürch
    TLDR Certain treatments can increase protein binding to natural hair but are less effective on permed hair.
    The study investigated methods to enhance the binding of keratin-associated proteins (KAP) and α-keratins (Ker) to hair fibers. Preactivation with 6-mercaptonicotinamide significantly improved binding to natural hair, and the presence of 25 mM L-arginine further increased Ker accumulation. Perming impaired Ker binding but had minimal effects on preactivated KAP, with enhanced penetrability observed in permed hair. The findings suggested that chemical modifications and additives, such as L-arginine and thiol preactivation, could improve keratin binding and hair restoration, informing the design of keratin-based hair care products.
    Discuss this study in the Community →

    Research cited in this study

    4 / 4 results

    Related Community Posts Join

    6 / 101 results

      community Comprehensive Microneedling Guide

      in Microneedling  295 upvotes 2 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community Keratin microspheres - breakthrough

      in Research/Science  13 upvotes 8 months ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community Results of Procyanidin B2 in clinical studies

      in Treatment  13 upvotes 4 years ago
      Procyanidin B2, a compound derived from Annurca apples, as a potential treatment for pattern hair loss. Several clinical studies were mentioned, which found that procyanidin B2 could increase hair growth, density, and keratin content. Other treatments such as Minoxidil, Finasteride, and RU58841 were not discussed.

      community Female Hair Loss, Is there anything else I should be doing?

       11 upvotes 10 years ago
      A 20-year old female experiencing hair loss, who has had normal blood tests and is currently using minoxidil as recommended by her doctor. She is asking if there are any other treatments she should consider.

      community Keratin fibers vs. Gossypium Herbaceum Hair fibers

      in Product  1 upvotes 2 months ago
      The conversation is about comparing keratin hair fibers to Gossypium Herbaceum hair fibers for diffuse hair loss. The user prefers keratin fibers for their durability and is seeking a bulk purchase option.

    Related Research

    1 / 1 results