TLDR Certain treatments can increase protein binding to natural hair but are less effective on permed hair.
The study investigated methods to enhance the binding of keratin-associated proteins (KAP) and α-keratins (Ker) to hair fibers. Preactivation with 6-mercaptonicotinamide significantly improved binding to natural hair, and the presence of 25 mM L-arginine further increased Ker accumulation. Perming impaired Ker binding but had minimal effects on preactivated KAP, with enhanced penetrability observed in permed hair. The findings suggested that chemical modifications and additives, such as L-arginine and thiol preactivation, could improve keratin binding and hair restoration, informing the design of keratin-based hair care products.
20 citations
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September 2018 in “Journal of colloid and interface science” Modified keratin binds better to hair, especially bleached hair.
115 citations
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August 2014 in “Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine” Human hair keratin can be used in many medical applications.
54 citations
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January 2013 in “Journal of Biological Macromolecules” A new method effectively separates keratin-associated proteins and keratin from human hair.
10 citations
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January 2012 in “Journal of Biological Macromolecules” Keratin film can effectively replace human hair for testing hair damage.
28 citations
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December 2011 in “Biocatalysis and biotransformation” PDI helps restore over-bleached hair's strength and structure by attaching special peptides.
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September 2011 in “Acta biomaterialia” Protein composition greatly affects the function of keratin biomaterials.
226 citations
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January 2002 in “Biological and Pharmaceutical Bulletin” A new method quickly extracts and identifies proteins from hair and other keratin sources.
1 citations
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December 2021 in “International journal of research in dermatology” Dermatologists should learn more about shampoos to better treat hair and scalp issues.
