Human Hair Keratin and Its-Based Biomaterials for Biomedical Applications

August 2014 in “ Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine ”

Hanna Lee, Kwantae Noh, Sang Cheon Lee, Il-Keun Kwon, Dong‐Wook Han, In-Seop Lee, Yu‐Shik Hwang

human hair keratin keratin hydrogels porous keratin scaffolds biocompatibility osseointegration tissue engineering drug delivery hemostatic properties

TLDR Human hair keratin can be used in many medical applications.

The document reviewed studies on human hair keratin and its biomedical applications, highlighting its use in drug permeation, ocular surface reconstruction, and enzymatic degradation. Keratin hydrogels supported sustained bioactive compound release and had hemostatic properties. Porous keratin scaffolds were promising for tissue engineering and drug delivery, showing biocompatibility and osseointegration in animal models. Overall, human hair keratin demonstrated significant potential as a versatile biomaterial for various medical applications.

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research The Use of Keratin Biomaterials Derived from Human Hair for the Promotion of Rapid Regeneration of Peripheral Nerves

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The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

research Characterization of the Lipid Composition at the Proximal Root Regions of Human Hair

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research Acidic and basic hair/nail ("hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins.

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Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Human Hair Keratin and Its-Based Biomaterials for Biomedical Applications

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research Mechanical and Biological Properties of Keratose Biomaterials

research Mechanisms of Hepatocyte Attachment to Keratin Biomaterials

research Keratin Hydrogels Support the Sustained Release of Bioactive Ciprofloxacin

research The Use of Keratin Biomaterials Derived from Human Hair for the Promotion of Rapid Regeneration of Peripheral Nerves

research The Hair Cycle

research Characterization of the Lipid Composition at the Proximal Root Regions of Human Hair

research Acidic and basic hair/nail ("hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins.