Keratin 16 Expression Defines a Subset of Epithelial Cells During Skin Morphogenesis and the Hair Cycle

    Kelsie M. Bernot, Pierre A. Coulombe, Kevin McGowan
    Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

    We don't know much about this study yet.

    Read the full study on jidonline.org →
    Discuss this study in the Community →

    Research cited in this study 17

    1. Hard and Soft Principles Defining the Structure, Function, and Regulation of Keratin Intermediate Filaments Current Opinion in Cell Biology · 2002
    2. Discovery of a Novel Murine Keratin 6 (K6) Isoform Explains the Absence of Hair and Nail Defects in Mice Deficient for K6a and K6b The Journal of Cell Biology · 2001
    3. Keratin 17 Expression in the Hard Epithelial Context of the Hair and Nail, and Its Relevance for the Pachyonychia Congenita Phenotype Journal of Investigative Dermatology · 2000
    4. Keratin Expression in the Normal Nail Unit: Markers of Regional Differentiation British Journal of Dermatology · 2000
    5. The Mouse Keratin 6 Isoforms Are Differentially Expressed in the Hair Follicle, Footpad, Tongue, and Activated Epidermis Differentiation · 1999
    6. The Functional Diversity of Epidermal Keratins Revealed by the Partial Rescue of the Keratin 14 Null Phenotype by Keratin 16 ˜The œjournal of cell biology/˜The œJournal of cell biology · 1999
    7. CDNA Cloning, Expression, And Assembly Characteristics Of Mouse Keratin 16 Journal of Biological Chemistry · 1998
    8. Onset of Keratin 17 Expression Coincides with the Definition of Major Epithelial Lineages During Skin Development The Journal of Cell Biology · 1998
    9. The Two Functional Keratin 6 Genes of Mouse Are Differentially Regulated and Evolved Independently from Their Human Orthologs Genomics · 1998
    10. Directed Expression of Keratin 16 to the Progenitor Basal Cells of Transgenic Mouse Skin Delays Skin Maturation The Journal of Cell Biology · 1998
    11. Localization of Plasminogen Activator Inhibitor Type 2 in Hair and Nail: Implications for Terminal Differentiation ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    12. Increased Expression of Keratin 16 Causes Anomalies in Cytoarchitecture and Keratinization in Transgenic Mouse Skin The Journal of Cell Biology · 1994
    13. The Secret Life of the Hair Follicle Trends in genetics · 1992
    14. A New Look Into an Old Problem: Keratins as Tools to Investigate Determination, Morphogenesis, and Differentiation in Skin Genes & Development · 1989
    15. A Group of Type I Keratin Genes on Human Chromosome 17: Characterization and Expression Molecular and Cellular Biology · 1988
    16. Acidic and Basic Hair/Nail (Hard) Keratins: Their Colocalization in Upper Cortical and Cuticle Cells of the Human Hair Follicle and Their Relationship to Soft Keratins ˜The œjournal of cell biology/˜The œJournal of cell biology · 1986
    17. Critical Stages of Hair Development and Pigmentation in the Mouse Physiological zoology · 1951

    Related research 7

    1. Reprogramming of Three-Dimensional Microenvironments for In Vitro Hair Follicle Induction bioRxiv (Cold Spring Harbor Laboratory) · 2022
    2. Morphogenesis, Growth Cycle, and Molecular Regulation of Hair Follicles Frontiers in Cell and Developmental Biology · 2022
    3. Expression and Localization of Sox10 During Hair Follicle Morphogenesis and Induced Hair Cycle International Journal of Medical Sciences · 2021
    4. Keratin 79 Identifies a Novel Population of Migratory Epithelial Cells That Initiates Hair Canal Morphogenesis and Regeneration Journal of Cell Science · 2013
    5. Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling Journal of Investigative Dermatology · 2012
    6. Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010
    7. Angora Mouse Mutation: Altered Hair Cycle, Follicular Dystrophy, Phenotypic Maintenance of Skin Grafts, and Changes in Keratin Expression Veterinary Pathology · 1997