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    Glossary Pluripotent Stem Cells

    cells that can develop into nearly any cell type

    Pluripotent Stem Cells (PSCs) are a type of stem cell that have the ability to develop into almost any cell type in the body, including skin, hair, and organ cells. This makes them incredibly valuable for medical research and regenerative medicine, as they can potentially be used to repair or replace damaged tissues and treat various conditions, including alopecia.

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    1. Hair-bearing human skin generated entirely from pluripotent stem cells Nature · 2020 · 425 citations
    2. Hair Follicle Development in Mouse Pluripotent Stem Cell-Derived Skin Organoids Cell Reports · 2018 · 169 citations
    3. Nestin‐positive hair follicle pluripotent stem cells can promote regeneration of impinged peripheral nerve injury The Journal of Dermatology · 2011 · 57 citations
    4. Development of pluripotent stem cell-derived epidermal organoids that generate effective extracellular vesicles in skin regeneration Biomaterials · 2024 · 25 citations
    5. Cryopreservation of Hair-Follicle Associated Pluripotent (HAP) Stem Cells Maintains Differentiation and Hair-Growth Potential Advances in experimental medicine and biology · 2016 · 4 citations
    6. Hair Follicle Dermal Cells Support Expansion of Murine and Human Embryonic and Induced Pluripotent Stem Cells and Promote Haematopoiesis in Mouse Cultures Stem cells international · 2018 · 3 citations
    7. Pluripotent Stem Cell Technology: A Promising Remedy for Hypopigmentation Disorders Journal of Stem Cell Research & Therapeutics · 2017 · 1 citations
    8. Applications of Human Pluripotent Stem Cell–Derived Skin Organoids in Dermatology 2023 · 1 citations
    9. Hair follicle associated pluripotent (HAP) stem cell from young mice have the greatest potential to differentiate to cardiac muscle cells Journal of dermatological science · 2017
    10. TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network Advanced Science · 2026
    11. 566 DermaCult™ Keratinocyte Expansion Medium, a Serum- and BPE-free Medium Supporting Long-term Feeder-free Expansion of Primary Human Epidermal and Pluripotent Stem Cell-Derived Keratinocytes Journal of Investigative Dermatology · 2022
    12. Human hair follicle pluripotent stem (hfPS) cells promote regeneration of peripheral‐nerve injury: An advantageous alternative to ES and iPS cells Journal of Cellular Biochemistry · 2009 · 121 citations
    13. Differentiation of Mouse Induced Pluripotent Stem Cells into a Multipotent Keratinocyte Lineage 2010 · 101 citations
    14. Generation of folliculogenic human epithelial stem cells from induced pluripotent stem cells Nature communications · 2014 · 99 citations
    15. Induced Pluripotent Stem Cells from Human Hair Follicle Mesenchymal Stem Cells Stem Cell Reviews and Reports · 2012 · 64 citations
    16. Nestin-Expressing Hair Follicle-Accessible Pluripotent Stem Cells for Nerve and Spinal Cord Repair Cells tissues organs · 2014 · 32 citations
    17. Reprogramming of Human Hair Follicle Dermal Papilla Cells into Induced Pluripotent Stem Cells Journal of Investigative Dermatology · 2012 · 26 citations
    18. Induced pluripotent stem cell line MUSIi006-A derived from hair follicle keratinocytes as a non-invasive somatic cell source Stem cell research · 2018 · 7 citations
    19. The Developmental & Molecular Requirements for Ensuring that Human Pluripotent Stem Cell-Derived Hair Follicle Bulge Stem Cells Have Acquired Competence for Hair Follicle Generation Following Transplantation Cell transplantation · 2021 · 4 citations
    20. Introduction to Hair-Follicle-Associated Pluripotent Stem Cells Methods in molecular biology · 2016 · 4 citations
    21. Stem Cells in Regenerative Medicine: A Journey from Adult Stem Cells to Induced Pluripotent Cells International Journal of Molecular Sciences · 2025 · 3 citations
    22. Peer Review #1 of "Induced pluripotent stem cells from human hair follicle keratinocytes as a potential source for in vitro hair follicle cloning (v0.1)" 2016
    23. 857 Human hair follicle regeneration with trichogenic human dermal papilla precursor cells derived from induced pluripotent stem cells Journal of Investigative Dermatology · 2017
    24. Roles of Melatonin in Goat Hair Follicle Stem Cell Proliferation and Pluripotency Through Regulating the Wnt Signaling Pathway Frontiers in Cell and Developmental Biology · 2021 · 11 citations
    25. From hair to heart: nestin-expressing hair-follicle-associated pluripotent (HAP) stem cells differentiate to beating cardiac muscle cells Cell Cycle · 2015 · 64 citations
    26. Isoproterenol directs hair follicle-associated pluripotent (HAP) stem cells to differentiate <i>in vitro</i> to cardiac muscle cells which can be induced to form beating heart-muscle tissue sheets 2016 · 29 citations
    27. Highly Pluripotent Adipose-Derived Stem Cell–Enriched Nanofat: A Novel Translational System in Stem Cell Therapy Cell Transplantation · 2023 · 28 citations
    28. Induced pluripotent stem cells from human hair follicle keratinocytes as a potential source for <i>in vitro</i> hair follicle cloning PeerJ · 2016 · 18 citations
    29. Induced pluripotent stem cells: Generation methods and a new perspective in COVID-19 research Frontiers in Cell and Developmental Biology · 2023 · 17 citations
    30. Hypoxia Enhances Differentiation of Hair Follicle-Associated-Pluripotent (HAP) Stem Cells to Cardiac-Muscle Cells Journal of Cellular Biochemistry · 2016 · 13 citations