Induced Pluripotent Stem Cell Line MUSIi006-A Derived from Hair Follicle Keratinocytes as a Non-Invasive Somatic Cell Source

    August 2018 in “ Stem cell research
    Bootsakorn Boonkaew, Lunnathaya Tapeng, Ratchapong Netsrithong, Chinnavuth Vatanashevanopakorn, Kovit Pattanapanyasat, Methichit Wattanapanitch
    TLDR Hair samples can be used to create stem cells easily and non-invasively.
    In this study, researchers successfully reprogrammed keratinocytes isolated from plucked hairs of a 21-year-old healthy woman into induced pluripotent stem cells (iPSCs) using Sendai virus. The resulting iPSC line, MUSIi006-A, was confirmed to be pluripotent, free from viral genome and transgenes, and retained a normal karyotype. This method demonstrated an easy, non-invasive, and efficient approach for generating iPSCs from hair samples, eliminating the need for medical professionals or operation rooms.
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