Chitosan in Dermatology: Applications and Benefits
January 2018
in “
Clinical dermatology open access journal
”
chitosan chitosan nanofibers chitosan nanoparticles chitosan hydrogels electrospinning wound dressings cell proliferation cell alignment cell reprogramming pluripotent stem cells alopecia treatment drug delivery systems wound healing cellular activity nanofibers nanoparticles hydrogels stem cells hair loss treatment drug delivery
TLDR Chitosan is useful in skin treatments because it helps with wound healing and cell growth.
Chitosan, a polysaccharide resembling the extracellular matrix, has been widely used in dermatology for its beneficial properties, including antibacterial characteristics. The document reviews the applications of chitosan in various forms such as nanofibers, nanoparticles, and hydrogels in dermatological treatments. Chitosan nanofibers, produced through electrospinning, have been effectively used in wound dressings to promote wound regeneration due to their ability to enhance cell proliferation and alignment. Chitosan nanoparticles have been employed in cell reprogramming to induce pluripotent stem cells, a novel method for alopecia treatment, and in drug delivery systems. Chitosan hydrogels, which can retain water and form a 3D network, accelerate wound healing and provide a conducive environment for cellular activity. The document concludes that the selection of the appropriate form of chitosan is crucial based on its final application in dermatology.
