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    Glossary Induced Pluripotent Stem Cells

    cells reprogrammed from adult cells to an embryonic-like state

    Induced Pluripotent Stem Cells (iPSCs) are a type of stem cell that scientists create by reprogramming adult cells, such as skin or blood cells, to revert to an embryonic-like state. This process allows these cells to potentially develop into any type of cell in the body, making them valuable for research, regenerative medicine, and disease modeling.

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    1. Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells Scientific Reports · 2017 · 42 citations
    2. Highly Efficient Neural Differentiation of CD34-Positive Hair-Follicle-Associated Pluripotent Stem Cells Induced by Retinoic Acid and Serum-Free Medium Methods in molecular biology · 2016 · 4 citations
    3. Hair Follicle Development in Mouse Pluripotent Stem Cell-Derived Skin Organoids Cell Reports · 2018 · 169 citations
    4. Generation of human-induced pluripotent stem cell-derived adherent 3-dimensional skin hair-follicle organoids Organoid · 2022 · 2 citations
    5. Induction of Skin-Derived Precursor Cells from Human Induced Pluripotent Stem Cells PLOS ONE · 2016 · 21 citations
    6. Induction of Pluripotent Stem Cells Via Wnt Signaling Pathway. eScholarship (California Digital Library) · 2013
    7. Functional regeneration strategies of hair follicles: advances and challenges Stem Cell Research & Therapy · 2025
    8. A novel and safe small molecule enhances hair follicle regeneration by facilitating metabolic reprogramming Experimental and Molecular Medicine · 2018 · 19 citations
    9. Generation of Induced Pluripotent Stem Cells from Hair Follicle Bulge Neural Crest Stem Cells Cellular reprogramming · 2014 · 3 citations
    10. Two Opposing Faces of Retinoic Acid: Induction of Stemness or Induction of Differentiation Depending on Cell-Type Biomolecules · 2019 · 41 citations
    11. 1418 Characterization of ectomesenchyme as an origin of epidermal stem cells Journal of Investigative Dermatology · 2023
    12. Adipogenic Differentiation of Canine Hair Follicle Stem Cells (cHFSCs) Indian Journal of Animal Research · 2022
    13. Stage‐specific regulation of Gremlin1 on the differentiation and expansion of human urinary induced pluripotent stem cells into endothelial progenitors Journal of Cellular and Molecular Medicine · 2020 · 3 citations
    14. Small Molecule Treatments Improve Differentiation Potential of Human Amniotic Fluid Stem Cells Frontiers in Bioengineering and Biotechnology · 2021 · 11 citations
    15. Reprogramming of human keratinocytes into functional cardiomyocytes Italian Journal of Anatomy and Embryology · 2026
    16. Pluripotent Stem Cell Technology: A Promising Remedy for Hypopigmentation Disorders Journal of Stem Cell Research & Therapeutics · 2017 · 1 citations
    17. Human pluripotent stem cell-derived skin organoids enabled pathophysiological model of Mycobacterium tuberculosis infection Nature Communications · 2025
    18. Generation of an integration-free human induced pluripotent stem cell line MUSIi010-A from occipital scalp fibroblasts of a male patient with androgenetic alopecia Stem Cell Research · 2019
    19. Valproic acid boosts hair follicle stem cell resilience to oxygen-glucose deprivation through autophagy induction and AKT/mTOR suppression Scientific Reports · 2025
    20. Induced Pluripotent Stem Cell Approach to Hair Follicle Regeneration Stem cell biology and regenerative medicine · 2022
    21. Isolation and Characterization of a Fetal-Maternal Microchimeric Stem Cell Population in Maternal Hair Follicles Long after Parturition Stem cell reviews · 2019 · 12 citations
    22. Function of KLF4 in Stem Cell Biology InTech eBooks · 2013 · 5 citations
    23. TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network Advanced Science · 2026
    24. Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation Journal of Cellular Biochemistry · 2011 · 37 citations
    25. The Developmental & Molecular Requirements for Ensuring that Human Pluripotent Stem Cell-Derived Hair Follicle Bulge Stem Cells Have Acquired Competence for Hair Follicle Generation Following Transplantation Cell transplantation · 2021 · 4 citations
    26. Applications of Human Pluripotent Stem Cell–Derived Skin Organoids in Dermatology 2023 · 1 citations
    27. Roles of Melatonin in Goat Hair Follicle Stem Cell Proliferation and Pluripotency Through Regulating the Wnt Signaling Pathway Frontiers in Cell and Developmental Biology · 2021 · 11 citations
    28. Development of pluripotent stem cell-derived epidermal organoids that generate effective extracellular vesicles in skin regeneration Biomaterials · 2024 · 25 citations
    29. Application and progress of induced pluripotent stem in chronic wound healing: a narrative review BMC Plastic and Reconstructive Surgery · 2026
    30. Highly Pluripotent Adipose-Derived Stem Cell–Enriched Nanofat: A Novel Translational System in Stem Cell Therapy Cell Transplantation · 2023 · 28 citations