Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

The study suggests that immune privilege collapse in bulge cells and the involvement of pro-inflammatory cytokine interferon-γ contribute to hair follicle stem cell loss in lichen planopilaris.

This study identified compound heterozygous mutations, c.1101del and c.736 T > A, in the LIPH gene responsible for causing autosomal recessive woolly hair in a child, with c.1101del being a novel frameshift mutation.

This study found that in Lichen Planopilaris, the Microbacteriaceae family was negatively correlated with IL-23 expression, suggesting a role in the disease's inflammation and microbiota composition.

This report identified a family of Iranian siblings with diverse clinical forms of Lichen Planus, suggesting potential genetic and environmental involvement in its pathogenesis.

This review discusses the essential roles and complex regulation of PP2A in various physiological processes and reports no clinical results; the authors highlight the need for further mouse model research to explore PP2A's therapeutic potential.

This manuscript reports on the first case of perforating necrobiosis lipoidica in Colombia, marking the 19th documented case worldwide.

This review discusses the role of lysophosphatidic acid in skin physiology and pathology, highlighting its significance in processes like wound healing and hair follicle development, but reports no new clinical findings.

This study reported that combining Poly-D,L-Lactic Acid with Platelet-Rich Plasma for facial rejuvenation reduced wrinkle severity and improved skin tone and hyperpigmentation in a 45-year-old female patient.

PPAR-γ agonists like pioglitazone may help manage lichen planopilaris but don't fully reverse scarring.

This review summarizes recent discoveries of GPCRs for lysophosphatidylserine and lysophosphatidylinositol, detailing their roles as lipid mediators, but reports no new experimental results.

This systematic review suggests that platelet-rich plasma may significantly improve symptoms in oral lichen planus with effects comparable to corticosteroids, although more research is needed to confirm these findings.

This review discusses the role of trichoscopy in diagnosing lichen planopilaris and reports no clinical results; the authors emphasize early recognition to potentially prevent permanent scarring.

GLABRA2 gene controls root-hair growth by regulating phospholipid signaling.

This study reported discovering a novel missense variant in a case of autosomal recessive woolly hair in a 31-year-old Chinese woman, which significantly reduced secretion of the encoded protein, likely leading to disease by impairing its hydrolytic function.

This report describes a unique case of linear lichen planus pigmentosus on the face with histological features of lichen planopilaris, which has not been documented before.

This case series describes five patients with rare facial lichen planopilaris, detailing the clinical presentation and treatment of their pigmentary changes and scarring alopecia.

This study suggests that combining tranexamic acid with low-dose oral retinoids may offer moderate to good improvements for lichen plan pigmentosus, although larger trials are needed for confirmation.

This article introduces the Progressive Loss (PL) Scale, aimed at helping physicians communicate the long-term cosmetic risks of hair restoration surgery to patients.

This study found that platelet lysate significantly improved hair growth and follicle performance in both experimental settings and AGA patients, showing results comparable to platelet-rich plasma.

Hair transplants can risk reactivating lichen planopilaris, a scarring hair loss condition.

This case report describes a 25-year-old woman with widespread lichen planus who did not respond to multiple systemic treatments, including antihistamines, hydroxychloroquine sulfate, and corticosteroids.

In this study, the P&P Hairline Laser, a hands-free laser-assisted device, was found to produce smoother and more symmetrical hairlines compared to traditional handheld laser devices.

This article discusses the importance of early recognition of LPP due to its significant aesthetic and psychosocial effects and calls for efforts to prevent misdiagnosis.

This review discusses the regulatory roles of lysophospholipids like LPA and S1P in diseases such as fibrosis, neuropathic pain, and cancer, but reports no new clinical results.

This study suggests a potential role for S100A7 and IL-17 in the pathogenesis of lichen planopilaris.

This case report highlights that early signs like pili torti may precede lichen planopilaris in some patients, emphasizing the importance of timely intervention to prevent permanent hair loss.

A specific mutation in PA-PLA1α causes abnormal hair growth.

In this study, researchers conducted a retrospective analysis of 16 cases of erosive palmoplantar lichen planus in North East India, finding a higher prevalence in pediatric and male patients, with common clinical features including plantar involvement and histopathological indicators such as basal cell degeneration.

This study reports that the loss of Langerhans cells in lichen planopilaris scars may be linked to the downregulation of ITG αvβ6, which is not seen in other scar formation diseases.

PLLA injections can cause hair loss and skin issues.