34 citations,
January 1989 in “Toxicologic Pathology” A study found that minoxidil can damage the hearts of dogs and pigs, cautioning its use in humans.
December 2021 in “Ad-Dawaa' Journal of Pharmaceutical Sciences” Green tea and celery leaf extracts in hair tonic promoted hair growth in guinea pigs, with the best results at specific concentrations.
March 2022 in “Journal of drug delivery and therapeutics” Sea hibiscus leaf extract at 30% concentration in a hair tonic significantly increased hair growth in guinea pigs.
6 citations,
February 2015 in “Journal of parasitic diseases” Ivermectin injections and spray, along with hygiene measures, successfully treated sarcoptic mange in guinea pigs.
2 citations,
March 2015 in “Toxicology and Environmental Health Sciences” Rice bran extract caused moderate skin irritation but no eye irritation, while a diluted essence was not irritating to skin and only slightly to guinea pigs.
53 citations,
June 2020 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Animal models help study psoriasis but have limitations and don't fully mimic the human disease.
28 citations,
January 2000 in “Medical Mycology” Fungal infections in lab animals can interfere with research.
14 citations,
January 2004 in “Journal of Biochemical and Molecular Toxicology” Mustard gas exposure causes hair loss, but treating with N-acetylcysteine can prevent it.
14 citations,
March 2020 in “Scientific Reports” Using dual-frequency ultrasound with microbubbles can potentially improve the delivery of hair growth treatment through the skin and enhance hair growth.
149 citations,
September 2017 in “Pharmaceutics” Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.
49 citations,
January 1991 in “Food and chemical toxicology” Different zinc compounds cause varying levels of skin irritation in animals.
4 citations,
April 2022 in “Microorganisms” Povidone iodine reduced skin bacteria more than chlorhexidine gluconate, but neither met FDA reduction standards.
2 citations,
January 2016 in “Skin pharmacology and physiology” Caragana korshinskii seed oil effectively treats fungal skin infections.
65 citations,
April 2000 in “The Laryngoscope” Clotrimazole, miconazole, and tolnaftate are likely safe, but gentian violet is risky.
43 citations,
January 1977 in “Toxicology and Applied Pharmacology” Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.
35 citations,
October 2017 in “Signal Transduction and Targeted Therapy” Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.
27 citations,
July 1946 in “The journal of nutrition/The Journal of nutrition” Biotin and inositol are crucial for pig health and growth.
22 citations,
August 2013 in “PLOS ONE” The method safely and efficiently delivers genes to the skin but may not work for conditions needing high levels of gene products.
15 citations,
June 1964 in “Experimental Biology and Medicine” Methotrexate can temporarily suppress certain immune responses without killing immune cells, potentially helping treat autoimmune diseases.
7 citations,
January 2022 in “Animal Reproduction” Using rodents for research shows that health problems in the womb can cause diseases later in life.
7 citations,
March 2017 in “Annals of Plastic Surgery” The new Mercedes flap variant effectively closed medium-sized scalp defects in a single operation with good cosmetic results and no complications.
5 citations,
October 2014 in “Journal of cosmetic and laser therapy” Combining physical dermabrasion with chemical peeling is more effective for skin treatment than chemical peeling alone.
1 citations,
October 2019 The 1:5 ratio of fragrant pandan to celery extract best promotes hair growth.
1 citations,
April 2017 in “Journal of Investigative Dermatology” SM04554 may increase hair growth as a topical treatment for androgenetic alopecia.
CRISPR/Cas9 gene-editing shows promise for livestock breeding but faces challenges like low efficiency and off-target effects.
February 2022 in “Research Square (Research Square)” LGR5 is a marker found in hair follicle stem cells in various species and is important for hair growth and skin repair.
Hibiscus leaf extract in hair tonic promotes hair growth effectively.
January 2008 in “Chinese Journal of Aesthetic and Plastic Surgery” Hair-derived material is safe and effective for skin filling.
276 citations,
December 2017 in “Journal of Dermatological Science” The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
69 citations,
September 1991 in “Journal of Surgical Research” Understanding how fetal wounds heal could help improve healing in adults.