A Small Molecule Modulator of the Wnt Pathway (SM04554) as a Potential Topical Treatment for Androgenetic Alopecia
May 2017
in “
Journal of Investigative Dermatology
”
TLDR SM04554 may increase hair growth as a topical treatment for androgenetic alopecia.
The document discusses the potential use of a small molecule modulator of the Wnt pathway, SM04554, as a topical treatment for androgenetic alopecia (AGA). Preclinical studies on male mice and mini-pigs showed that SM04554 increased follicle numbers and hair growth compared to vehicle, indicating its potential as a topical therapy for AGA. Clinical studies were ongoing at the time of the document's publication.
