1 citations
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April 2023 in “Animals” In this study, Min pigs were found to have unique characteristics for secondary hair growth compared to Berkshire and Yorkshire pigs, with the Wnt and BMP signaling pathways stimulating follicle stem cell activity and promoting secondary hair growth and gene expression.
July 2023 in “Turkish journal of veterinary research” This study investigated the hair structure of wild pigs in the Balıkesir region using stereomicroscopy and scanning electron microscopy, finding distinct bifurcation patterns, but concluded that pig bristles used in brushes likely wouldn't retain these features, complicating species identification.
April 2016 in “Journal of Investigative Dermatology” This study found that full thickness wounds in Lanyu pigs led to altered molecular expression and abnormal skin structure, without regenerating key epithelial cells thought to aid in skin regeneration.
January 2010 in “HAL (Le Centre pour la Communication Scientifique Directe)” This study found that intra-cochlear administration of z-VAD-FMK for 7 days after gunshot noise trauma in guinea pigs accelerated hearing recovery and preserved hair cell survival.
63 citations
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December 2010 in “Journal of Endocrinology” This study found that decreased allopregnanolone levels through inhibition or intrauterine growth restriction in guinea pigs were linked to altered brain development markers, suggesting a role for neurosteroids in fetal brain protection and development.
35 citations
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January 2001 in “Journal of Animal Science” This study found that dietary selenium levels above 5 ppm can lead to selenosis in pigs, with white-haired pigs showing alopecia sooner than dark-haired pigs.
24 citations
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December 1957 in “Experimental Cell Research” This study observed that the glassy layer of hair follicles in guinea pigs consists of thick collagen-type fibrils organized into two distinct arrays, whereas in young mice, the fibrils are thinner and develop between the outer root sheath and fibroblasts.
15 citations
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January 2019 in “Experimental Dermatology” In this study, full-thickness wounding on Lanyu pigs led to scar formation and disrupted cell markers, while partial-thickness wounding allowed limited regeneration of rete ridges and papillary dermis.
15 citations
,
November 1994 in “International Journal of Dermatology” This study found that while the combination of oral propranolol and intradermal injections in guinea pigs led to psoriasiform changes, it did not fully mimic psoriasis.
5 citations
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September 2019 in “Journal of Biomedical Optics” This study determined in-vivo skin damage thresholds for 1319-nm laser exposure in pigs, and the findings may enhance understanding of thermal damage mechanisms and inform laser safety standards.
2 citations
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January 1973 in “ACTA HISTOCHEMICA ET CYTOCHEMICA” In this study, the brown skin of guinea pigs exhibited higher levels of certain biochemical markers related to melanogenesis compared to black and white skin, with distinct differences in ascorbic acid utilization and protein concentrations observed between regions.
November 2024 in “Journal of Cosmetic Dermatology” This study found that valproic acid-loaded microemulsion formulations enhanced skin penetration pathways in guinea pigs compared to an aqueous solution, with composition elements like oil content and surfactant ratios significantly affecting drug delivery performance.
November 2023 in “Applied sciences” This study found that platelet dry powder can be mass-produced from pig blood by adding calcium chloride, resulting in a stable material with high growth factor concentrations, which could enhance supply for industrial product development.
January 2010 in “Pharmacy Today” This study found that collagen and its compound may have antioxidant effects and reduce melanin in guinea pigs, while increasing skin moisture and hydroxyproline content in mice.
60 citations
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January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that inhibiting PKC-β activity with bisindolylmaleimide reduces pigmentation in the skin and hair of guinea pigs and mice by preventing tyrosinase activation.
30 citations
,
July 1984 in “Journal of Animal Science” In this study, sows fed a diet with added biotin weaned more pigs per litter overall, though other reproductive and health metrics showed no improvement.
26 citations
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September 2014 in “Neuroscience Letters” This study found that metformin did not prevent gentamicin-induced hearing loss and even worsened auditory threshold shifts and caused adverse effects at higher doses in guinea pigs.
22 citations
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August 2013 in “PLOS ONE” This study found that using a non-invasive multielectrode array for gene electrotransfer in hairless guinea pigs increased gene expression in the epidermis significantly, with minimal skin changes observed.
22 citations
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September 1986 in “Journal of Investigative Dermatology” This study found that low-dose topical alpha-terthienyl combined with UVA radiation can induce cutaneous photosensitization in guinea pigs, suggesting a possible photochemotherapy approach for skin diseases like psoriasis.
15 citations
,
June 1964 in “Experimental Biology and Medicine” This study found that methotrexate treatment for 15 days suppressed tuberculin hypersensitivity in Strain 2 guinea pigs without causing lymphopenic or anti-inflammatory effects.
12 citations
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January 1999 in “Journal of Animal Science” This study observed that combined treatment with thyroxine and hydrocortisone increased lipid accretion and fat cell development in hypophysectomized fetal pigs, suggesting a key role of these hormones in fetal adipogenesis.
11 citations
,
November 2019 in “The FASEB Journal” In this study, a missense mutation in the MAP2 gene was found to be associated with reduced hair follicle density, leading to the hairless phenotype in pigs.
3 citations
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April 2015 in “International research journal of pharmacy” This study concluded that the follicular route is a significant pathway for delivering gentamicin through the skin, as demonstrated by higher drug permeation in non-plugged pig's ear skin compared to plugged skin.
1 citations
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August 2025 in “Bioengineering” In this study, the combination of full-thickness skin column grafts and the TSN6 peptide improved wound healing quality in pigs by enhancing epidermal maturation compared to other treatments.
1 citations
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January 2022 in “Indonesian Journal of Pharmaceutical Science and Technology” This study evaluated a 20% cinchona extract cream and found it increased hair growth length and mass in guinea pigs, demonstrated good physical stability, and did not irritate rabbit skin.
1 citations
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January 2019 This study found that a hair tonic combining fragrant pandan and celery extracts increased hair length in guinea pigs, with the 1:5 concentration showing the best growth activity.
1 citations
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March 2013 in “Revista de Investigaciones Veterinarias del Perú” This study found that a single application of 0.1% aqueous benzalkonium chloride solution effectively treated dermatomycosis caused by Trichophyton species in guinea pigs.
October 2024 in “AL-MIKRAJ Jurnal Studi Islam dan Humaniora (E-ISSN 2745-4584)” This study found that a hair tonic made with 30% ethanol extract from papaya fruit peel effectively promoted hair growth in guinea pigs, with results close to those of a positive control, and contains beneficial compounds like alkaloids and flavonoids.
December 2022 in “Experimental and Clinical Physiology and Biochemistry” This study found that a lotion with 5% minoxidil significantly altered immune parameters and disrupted immunological balance in guinea pigs, suggesting a substantial impact on both cellular and humoral immunity.
March 2022 in “Journal of drug delivery and therapeutics” Sea hibiscus leaf extract at 30% concentration in a hair tonic significantly increased hair growth in guinea pigs.