19 citations
,
June 2020 in “General and comparative endocrinology” This study found that hair cortisol concentration is a promising stress indicator in cattle but not in pigs, where external factors and lower cortisol response may interfere with its validity.
8 citations
,
December 2020 in “Scientific reports” This study examined the genetic basis for the curly hair trait in Mangalitza pigs, finding two specific genetic variants that contribute to this distinctive phenotype through autosomal dominant inheritance.
7 citations
,
March 2022 in “Scientific reports” In this study, researchers found that pigs with genetically disrupted ANTXR1 were resistant to Senecavirus A infection, showing no clinical symptoms, and provided a model for human GAPO syndrome, while confirming ANTXR1 as a receptor for the virus.
This review discusses potential causes and diagnostic tools for alopecia in guinea pigs and highlights the need to evaluate diet and housing, but it reports no original findings.
February 2019 in “Veterinarski glasnik” Guinea pigs' skin issues in the lumbar area may be caused by dermatological problems and need proper care.
August 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study characterizes the secondary hair follicles in the Lanyu pig, an indigenous breed sharing similarities with human vellus hair follicles, suggesting its relevance as a model for researching hair follicle-mediated skin regeneration and enhancing translation to human wound healing.
23 citations
,
August 1989 in “American Journal of Veterinary Research” In this study, high selenium diets from different sources caused weight and hair loss in pigs, with additional hoof and coronary band problems particularly in those fed sodium selenate.
14 citations
,
February 2011 in “Drug Metabolism and Disposition” This study examined the pharmacokinetics of finasteride in pigs and found that ketoconazole coadministration affected its distribution across various plasma compartments, bile, and urine.
8 citations
,
March 2013 in “Cell Transplantation” In this study, intradermal injection of GCSF-mobilized peripheral blood stem cells from young pigs rejuvenated skin in aged pigs by increasing collagen, elastin, and cell renewal rates.
5 citations
,
May 1952 in “Journal of Animal Science” This study found that supplementing baby pigs with riboflavin relieved external symptoms of deficiency, but many internal issues persisted, possibly due to inadequate dosage or treatment duration.
November 2025 in “BMC Genomics” This study found that the systemic wrinkled skin phenotype in Xiang pigs involves gene expression changes and genetic variations associated with oxidative stress and extracellular matrix components, resembling features seen in Shar-Pei dogs.
January 2007 in “Pizhūhish va sāzandigī” This study describes the characteristics and potential research applications of the first hairless guinea pigs in Iran, noting their suitability for allergy, dermal, transplantation, and immunology studies.
13 citations
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February 1951 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” This study found that daily supplementation with 10 to 20 mg of calcium pantothenate led to complete recovery and significant improvement in appetite and growth in young pigs with pantothenic acid deficiency.
12 citations
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February 2017 in “International journal of developmental neuroscience” This study observed that reduced in utero exposure to the neurosteroid allopregnanolone increased anxiety-like behavior in female guinea pigs during the juvenile period without affecting long-term allopregnanolone levels.
February 2025 in “Eduvest - Journal Of Universal Studies” In a laboratory study on guinea pigs, Kepok banana peel extract serum at a 30% concentration showed promising effectiveness for hair growth, with results close to those of 5% minoxidil®, suggesting it could be a viable hair care alternative.
This research developed a pig graph pangenome assembly of 27 genomes, revealing the importance of structural variations in adaptation and breed-specific traits, with BTF3 identified as a key gene influencing intramuscular fat and meat quality.
September 2024 in “Genes” This study found significant genetic differences between pigs with and without hair whorls, suggesting potential implications for pig breeding strategies in China.
August 2004 in “Veterinary Dermatology” This case report describes two guinea pigs infested with Acarus farris mites, which were successfully treated with Phoxim and removal of contaminated hay, leading to rapid resolution of skin lesions and alopecia.
53 citations
,
November 1997 in “Journal of Forensic Sciences” This study found that codeine incorporation in guinea pig hair varied with pigmentation and was highest in black hair, suggesting the role of eumelanins in drug binding.
27 citations
,
July 1946 in “The journal of nutrition/The Journal of nutrition” This study found that adding inositol or biotin to a pig's diet without sulfathalidine had no effect on growth or feed efficiency, but both helped alleviate deficiency symptoms caused by sulfathalidine.
16 citations
,
January 2021 in “Frontiers in veterinary science” This study found no significant difference in hair cortisol concentrations, a chronic stress indicator, between sows in farrowing crates and those in loose-housing systems.
13 citations
,
March 1997 in “Research in Veterinary Science/Research in veterinary science” This study found that epithelial keratin K 6 is associated with hyperkeratotic and ulcerated changes in the gastric pars oesophagea of pigs, suggesting epithelial proliferation plays a role in ulcer development.
7 citations
,
June 2001 in “PubMed” This study details the histological structure of the white domesticated pig's ear skin and discusses its relevance as a model for human dermatological research.
3 citations
,
December 2007 in “Journal of Otology” This study found that adipose-derived stem cells from adult guinea pigs can differentiate into hair cell-like cells in vitro, suggesting potential use in tissue engineering.
3 citations
,
December 1994 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” In this study, itraconazole was shown to accumulate in the deeper skin layers of guinea pigs after oral administration, suggesting this delivery method effectively targets infective organisms there.
1 citations
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January 1972 in “PubMed”
November 2023 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” In this study, researchers examined the genetic factors impacting cortisol and DHEA concentrations in the hair of healthy pigs; they found that cortisol levels were heritable and genetically correlated with behavioral stress responses, suggesting these hormones could potentially serve as indicators for selecting disease-resilient pigs.
June 2023 in “Frontiers in Genetics” This study suggests that the curly hair phenotype in Mangalitza pigs may involve complex gene interactions related to calcium signaling and lipid metabolism, rather than changes in TRPM2 or CYP4F3 expression.
April 2023 in “Experimental Dermatology” This study found that a single intradermal injection of human dermal papilla cells increased hair follicle number and thickness in pigs, suggesting potential effectiveness for hair growth in humans.
November 2022 in “PubMed” This study found that inadequate thickness of deep dermal tissue in pigs is a key factor leading to fibrosis, with fibrosis likely serving a compensatory function for skin thickness.