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Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Targeting TGFβ can improve skin immunity in older people.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

New therapies are being developed that target integrin pathways to treat various diseases.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.

MicroRNA-21 could help diagnose and treat skin fibrosis.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.

Chrysin makes docetaxel more effective and reduces its side effects in lung cancer treatment.

The review suggests that a special cell-derived treatment shows promise for various skin conditions and hair growth but needs more research for confirmation.

Targeted anticancer therapies in children often cause skin side effects like rash and dry skin.

Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.

TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.

Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

HB-EGF boosts the hair growth ability of stem cells, making it a potential hair loss treatment.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.

circRNA-1926 helps goat stem cells turn into hair follicles by affecting miR-148a/b-3p and CDK19.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.

Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.

Lindera aggregata has many beneficial compounds that can help prevent and manage diseases.

High mTORC1 activity slows hair growth and causes it to lose color.

Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

Marine algae compounds may improve skin health and promote hair growth.

Intermediate filaments are crucial for cell differentiation and stem cell function.

Autophagy helps keep skin healthy and may improve treatments for skin diseases.