A Review on the Chemical Constituents and Pharmacological Efficacies of Lindera Aggregata (Sims) Kosterm

Lindera aggregata (L. aggregata) is a traditional medicinal plant with diverse bioactive compounds, including sesquiterpenoids, alkaloids, flavonoids, and essential oils, which contribute to its significant pharmacological activities. These include anti-inflammatory, anti-tumor, hepatoprotective, and anti-hyperlipidemic effects. The plant's extracts have shown potential in treating various conditions such as cancer, inflammatory diseases, liver and kidney injuries, osteoporosis, insulin resistance, and androgenetic alopecia. Key mechanisms involve modulation of lipid metabolism, antioxidant activity, and immune responses. Despite extensive studies, further research is needed to fully understand its phytochemical composition, pharmacological mechanisms, and safety profile.