research Adenosine A2B Receptor: A Pathogenic Factor and a Therapeutic Target for Sensorineural Hearing Loss
Blocking adenosine A2B receptor may prevent or treat hearing loss.
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research Controversies in Off-Label Prescriptions in Dermatology: The Perspective of the Patient, the Physician, and the Pharmaceutical Companies
The document concludes that doctors should carefully consider off-label drug use in dermatology and always inform patients, while more research is needed on the safety and effectiveness of such practices.
research Nutraceuticals for Healthy Skin Aging
Certain nutrients can help keep skin healthy as we age.
research Efficacy and Safety of Different JAK Inhibitors in the Treatment of Alopecia Areata: A Network Meta-Analysis
Oral baricitinib and ruxolitinib are effective and safe for treating alopecia areata.
research Drug Safety Evaluation of Exemestane
Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.
research Smoothened Antagonists for Hair Inhibition
Two new compounds were found to effectively reduce hair growth in mice.
research Therapeutic Control of Androgen Action
Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
research Determination of Finasteride and Its Metabolite in Urine by Dispersive Liquid-Liquid Microextraction Combined with Field-Enhanced Sample Stacking and Sweeping
New method accurately measures finasteride and M3 in urine, helping evaluate pharmacokinetics.
research Use of Adapalene in Alopecia Areata: Efficacy and Safety of Mometasone Furoate 0.1% Cream Versus Combination of Mometasone Furoate 0.1% Cream and Adapalene 0.1% Gel in Alopecia Areata
Combining mometasone furoate cream with adapalene gel is safer and more effective for hair regrowth in alopecia areata than using the cream alone.
research Indian Gooseberry (Emblica Officinalis Gaertn.) Pharmacological Properties
Indian Gooseberry has potential for cancer prevention and treatment and promotes hair growth.
research Correction of Hair Shaft Defects Through Allele-Specific Silencing of Mutant Krt75
Using special RNA to target a mutant gene fixed hair problems in mice.
research Early Dengue Virus Infection in Human Skin: A Cycle of Inflammation and Infectivity
Chicken feather gene mutation helps understand human hair disorders.
research Differential Impact of Environmental Factors on Systemic and Localized Autoimmunity
Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.
research Evaluating Antiinflammatory and Antiandrogenic Effects of Garden Cress (Lepidium Sativum L.) in HaCaT Cells
Garden cress extract may help treat skin inflammation and androgen-related disorders.
research Hair Follicle Targeting with Nanoparticles
Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.
research Inhibition of T-Cell Activity in Alopecia Areata: Recent Developments and New Directions
New treatments targeting T-cell pathways are needed for better alopecia areata management.
research Drug-Induced Gynecomastia: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.
research Imaging Prostate Cancer With Technetium-99m Tricarbonyl Finasteride Dithiocarbamate
A new compound was effective for imaging prostate cancer in rats.
research An Accessible Pharmacodynamic Transcriptional Biomarker for Notch Target Engagement
Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.
research Radiation-Induced Alopecia After Endovascular Embolization Under Fluoroscopy
A man had temporary hair loss from radiation during a medical procedure but regrew his hair after treatment with minoxidil lotion.
research Impact of Clinical Response on Different Approved Doses in Japan and the United States
Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.
research Footprints of the EADV: A Meeting Report from the 17th Congress of the European Academy of Dermatology and Venereology
The conference highlighted new dermatological treatments and emphasized early intervention and addressing conditions lacking evidence-based treatments.
research Novel Electroporation-Based Treatments for Breast Cancer
Electric pulse treatments for breast cancer show promise in being safer and more effective, with fewer side effects.
research Beta-Caryophyllene Enhances Wound Healing Through Multiple Routes
Beta-caryophyllene, found in essential oils, helps wounds heal better in multiple ways.
research Topical Treatment with the Bacterium-Derived c-Met Agonist InlB321/15 Accelerates Healing in the Abrasion Wound Mouse Model
Applying InlB321/15 to wounds sped up healing in mice.
research The Conception and Evaluation of Sexual Health Literature
The document concludes that better research methods are needed in men's sexual health to provide stronger evidence and improve patient care.
research Cytokines
Cytokines are important for immune responses and treating diseases, but they can cause side effects like fever and skin issues.
research Alopecia Associated With Zidovudine Therapy
Zidovudine may cause hair loss in advanced-stage HIV patients.
research Gut Microbiome, Metabolome and Alopecia Areata
The health of the gut may be important in developing new ways to prevent, diagnose, and treat alopecia areata.
research Influence of Saw Palmetto and Pygeum Africana Extracts on the Urinary Concentrations of Endogenous Anabolic Steroids: Relevance to Doping Analysis
Taking Saw palmetto and Pygeum africana can change the levels of certain steroids in urine, which could cause confusion in doping tests.