Novel Electroporation-Based Treatments for Breast Cancer

Electroporation-based treatments, such as Electrochemotherapy (ECT) and Irreversible Electroporation (EP), are emerging as promising methods for breast cancer (BC) treatment. These methods involve using electric pulses to enhance the efficacy of cytostatic drugs or to directly affect tumor cells, potentially allowing for lower doses of drugs and reducing side effects like nausea, hair loss, and fertility disorders. Research indicates that EP-based treatments can be safer and more effective than traditional treatments, and they have been applied to both primary breast cancer and its metastases. Additionally, these treatments have demonstrated palliative benefits, including pain reduction in patients.