Cytokines

    July 1996 in “ Clinics in Dermatology ”
    Joseph P. Shrum
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    TLDR Cytokines are important for immune responses and treating diseases, but they can cause side effects like fever and skin issues.
    The 1996 document describes cytokines as glycoproteins that play a crucial role in inflammatory and immunological responses, with significant implications in dermatology. It details the therapeutic uses and side effects of various cytokines, including erythropoietin (EPO), colony-stimulating factors (CSFs), interleukins (ILs), and tumor necrosis factors (TNFs). EPO has been used to treat anemia, with side effects that include improved hair texture and growth. CSFs can cause fever, alopecia, and psoriasis exacerbation. ILs are involved in immune response and cancer treatment, with side effects like fever and skin reactions. TNF-α, used in cancer therapy, can be cytotoxic to tumors and has side effects such as fever and chills, but can also lead to serious complications like septic shock. The document also discusses skin issues related to nutrient deficiencies and obesity, emphasizing the importance of addressing underlying health problems for long-term improvement.
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