Adenosine A2B Receptor: A Pathogenic Factor and a Therapeutic Target for Sensorineural Hearing Loss

    December 2020 in “ The FASEB Journal ”
    Jeanne M. Manalo, Hong Liu, Dalian Ding, John Hicks, Hong Sun, Richard Salvi, Rodney E. Kellems, Fred A. Pereira, Yang Xia
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    TLDR Blocking adenosine A2B receptor may prevent or treat hearing loss.
    The adenosine A2B receptor is a potential therapeutic target for sensorineural hearing loss, as blocking it may prevent or treat hearing loss. Studies on mice suggest that elevated adenosine levels can cause nerve fiber demyel
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