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The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

Indian Gooseberry has potential for cancer prevention and treatment and promotes hair growth.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Garden cress extract may help treat skin inflammation and androgen-related disorders.

EtG in hair can help detect alcohol use but may be inaccurate in people with certain health conditions.

Taking Dutasteride with Ketoconazole can increase Dutasteride's effects and side effects.

Topical minoxidil does not change the activity of hair follicle enzymes that metabolize it.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Human hair shows promise for non-invasive medical testing, but more research is needed to standardize its use.

Good nutrition is crucial for health and preventing disease, and supplements can help prevent nutrient deficiencies.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.

Researchers created artificial human skin using special cells, which could help treat skin conditions like albinism and vitiligo.

Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.

Topical JAK inhibitors may help treat alopecia universalis by promoting hair regrowth.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Dutasteride improved hair density and thickness in men not helped by finasteride, with minimal side effects.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.

Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Flavonoids in Iraqi marshland plants have potential health benefits like antioxidant and anti-inflammatory effects.